Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 10/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042872 | 0.87 | P2RX7 (0.44) | PROKR1P2RX7CFTRCHRM4CNR1 | |
| SCHEMBL20043089 | 0.84 | P2RX7 (0.52) | PROKR1P2RX7CHRM4LMNASMN1; SMN2 | |
| SCHEMBL20042697 | 0.84 | PROKR1 (0.48) | PROKR1P2RX7CFTRCHRM4CNR1 | |
| SCHEMBL20042671 | 0.82 | P2RX7 (0.45) | P2RX7CNR1CNR2GPR55SMN1; SMN2 | |
| SCHEMBL20042698 | 0.81 | MEN1 (0.43) | P2RX7POLBCFTRCNR1CNR2 | |
| SCHEMBL20042668 | 0.81 | HPGD (0.51) | P2RX7LMNASMN1; SMN2 | |
| SCHEMBL20042776 | 0.81 | P2RX7 (0.41) | P2RX7MTORCFTRCNR1CNR2 | |
| SCHEMBL20042839 | 0.80 | P2RX7 (0.45) | P2RX7MTORCFTRCNR1CNR2 | |
| SCHEMBL20042743 | 0.80 | P2RX7 (0.40) | PROKR1P2RX7CYP1A2MTORCHRM4 | |
| SCHEMBL20042817 | 0.80 | PKM (0.44) | P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |