Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042760 | 0.86 | P2RX7 (0.45) | MEN1KMT2AP2RX7GBA1ABL1 | |
| SCHEMBL20042776 | 0.86 | P2RX7 (0.41) | LMNAMEN1KMT2AP2RX7TSHR | |
| SCHEMBL20042817 | 0.86 | PKM (0.44) | ALDH1A1LMNAMEN1KMT2AP2RX7 | |
| SCHEMBL20042832 | 0.86 | CFTR (0.45) | ALDH1A1LMNAMEN1KMT2AP2RX7 | |
| SCHEMBL20042872 | 0.84 | P2RX7 (0.44) | LMNAP2RX7SMN1; SMN2GBA1HSD17B10 | |
| SCHEMBL20042751 | 0.84 | HSD17B10 (0.49) | ALDH1A1LMNAMEN1KMT2AP2RX7 | |
| SCHEMBL20042685 | 0.84 | HTT (0.42) | GRM5P2RX7SMN1; SMN2GBA1ABL1 | |
| SCHEMBL20042839 | 0.84 | P2RX7 (0.45) | ALDH1A1MEN1KMT2AP2RX7TSHR | |
| SCHEMBL20042743 | 0.84 | P2RX7 (0.40) | P2RX7TSHRSMN1; SMN2GBA1HPGD | |
| SCHEMBL20042756 | 0.83 | P2RX7 (0.38) | ALDH1A1LMNAMEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |