Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17136028 | 0.83 | HSD17B10 (0.64) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL11035155 | 0.81 | HSD17B10 (0.62) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL2042234 | 0.80 | NSD2 (0.66) | KDM4EHSD17B10HPGDALDH1A1MEN1 | |
| SCHEMBL3722103 | 0.80 | HSD17B10 (0.60) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL13770170 | 0.80 | HPGD (0.60) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL3632164 | 0.80 | HSD17B10 (0.60) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL1145013 | 0.80 | HPGD (0.60) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL1144741 | 0.80 | HPGD (0.60) | KDM4ETDP1HSD17B10HPGDALDH1A1 | |
| SCHEMBL10509208 | 0.80 | XDH (0.50) | KDM4ETDP1DAOGRIN2DGRIN2A | |
| SCHEMBL10506723 | 0.79 | HPGD (0.49) | KDM4ETDP1HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115701440-A | Polyimide composite film, preparation method thereof and electronic equipment | 华为技术有限公司 | 2023-02-10 | — | — | CN | claimed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110643032-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| US-20260060959-A1 | FORMULATIONS WITH REDUCED OXIDATION | GENENTECH INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-20230181533-A1 | FORMULATIONS WITH REDUCED OXIDATION | GENENTECH INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11596620-B2 | Formulations with reduced oxidation | F. HOFFMANN-LA ROCHE AG (CH) | 2023-03-07 | — | — | US | disclosed |
| CN-115701440-A | Polyimide composite film, preparation method thereof and electronic equipment | 华为技术有限公司 | 2023-02-10 | — | — | CN | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-11267825-B2 | Highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis B virus (HBV) | AICURIS GMBH & CO. KG (DE) | 2022-03-08 | — | — | US | disclosed |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | GENENTECH, INC. (US) | 2022-02-17 | — | — | US | disclosed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| EP-2049520-A2 | INDOLE COMPOUNDS | Ironwood Pharmaceuticals, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008019357-A2 | INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |
| US-4835175-A | Indole derivatives pharmaceutical preparations based thereon, and β-receptor stimulation therewith | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0062919-B1 | INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0062919-A1 | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060959-A1 | FORMULATIONS WITH REDUCED OXIDATION | LPO, SET, PTMS | KDM4E 1738/4885TDP1 4559/4885HSD17B10 1774/4885 |
| US-11596620-B2 | Formulations with reduced oxidation | PRDX5, PRDX3, LPO | KDM4E 3145/4885TDP1 3432/4885HSD17B10 472/4885 |
| US-20220047711-A1 | PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO FC-CONTAINING PROTEINS | FCGR2A, FCGR3B, DNPEP | KDM4E 4325/4885TDP1 3373/4885HSD17B10 3056/4885 |
| US-20230181533-A1 | FORMULATIONS WITH REDUCED OXIDATION | PRDX5, PRDX3, LPO | KDM4E 3145/4885TDP1 3432/4885HSD17B10 472/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | KDM4E 4115/4885TDP1 4223/4885HSD17B10 1914/4885 |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | FAAH, FAAH2, AANAT | KDM4E 2232/4885TDP1 1782/4885HSD17B10 548/4885 |
| US-11267825-B2 | Highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis B virus (HBV) | HCCS, BRD4, IDO2 | KDM4E 578/4885TDP1 3811/4885HSD17B10 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.