Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6145 | 0.82 | KCNN4 (0.58) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Fluoride SCHEMBL634655 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Water SCHEMBL4609376 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL111457 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL8387827 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Iodide SCHEMBL6672017 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Bromide SCHEMBL3629993 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Bromide SCHEMBL414533 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Methylamine SCHEMBL20916863 | 0.80 | KCNN4 (0.55) | KCNN4TSHRTAAR1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL8387706 | 0.78 | KCNN4 (0.52) | KCNN4TSHRTAAR1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800782-B2 | Inhibitors of cellular metabolic processes | Agios Pharmaceutical, Inc. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190233424-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2019-08-01 | — | — | US | disclosed |
| CN-105473576-A | Pyrimidinedione compounds for cardiac disorders | MYOKARDIA INC | 2016-04-06 | — | — | CN | disclosed |
| CN-101952244-B | N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors | AMIRA PHARMACEUTICALS INC | 2014-11-05 | — | — | CN | disclosed |
| CN-103998429-A | Substituted anilines as ccr(4) antagonists | CHEMOCENTRYX INC | 2014-08-20 | — | — | CN | disclosed |
| CN-103974950-A | Substituted benzimidazoles and benzopyrazoles as CCR(4) antagonists | CHEMOCENTRYX INC | 2014-08-06 | — | — | CN | disclosed |
| CN-103958487-A | Benzoic acid derivatives as eif4e inhibitors | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| EP-1857471-B1 | POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER | MITSUI CHEMICALS INC (JP) | 2013-04-24 | — | — | EP | disclosed |
| CN-102985489-A | Method for producing polyphenylene ether resin composition | MITSUBISHI ENG PLASTICS CORP | 2013-03-20 | — | — | CN | disclosed |
| CN-101033293-B | Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof | MITSUBISHI GAS CHEMICAL CO | 2011-11-16 | — | — | CN | disclosed |
| CN-1914239-B | Curable resin composition | NIPPON STEEL CHEMICAL CO | 2010-05-05 | — | — | CN | disclosed |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | disclosed |
| US-20080177014-A1 | Polymerization Catalyst Composition and Process for Production of Polymer | MITSUI CHEMICALS, INC. (JP) | 2008-07-24 | — | — | US | disclosed |
| CN-101128491-A | Polymerization catalyst composition and method for producing polymer | MITSUI CHEMICALS INC (JP) | 2008-02-20 | — | — | CN | disclosed |
| EP-1857471-A1 | POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER | Mitsui Chemicals, Inc. (JP) | 2007-11-21 | — | — | EP | disclosed |
| CN-101033293-A | Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof | MITSUBISHI GAS CHEMICAL CO (JP) | 2007-09-12 | — | — | CN | disclosed |
| CN-1964748-A | Coating compositions for bioactive agents | SURMODICS INC (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1964749-A | Coating compositions for bioactive agents | SURMODICS INC (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1964750-A | Bioactive coating compositions for medical devices | SURMODICS INC (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1914239-A | Curable resin composition | NIPPON STEEL CHEMICAL CO (JP) | 2007-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | KCNN4 3138/4885TSHR 3648/4885TAAR1 3251/4885 |
| US-20190233424-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | MNAT1, MAT2A, PCK2 | KCNN4 4816/4885TSHR 2620/4885TAAR1 3750/4885 |
| US-10800782-B2 | Inhibitors of cellular metabolic processes | MNAT1, MAT2A, PCK2 | KCNN4 4816/4885TSHR 2620/4885TAAR1 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.