SCHEMBL2006751

SCHEMBL2006751

CCC(=O)Oc1cn(Cc2ccccc2)c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
LMNA P02545 1/20 0.56
MAPK1 P28482 2/20 0.53
NPSR1 Q6W5P4 2/20 0.52
ADORA1 P30542 1/20 0.51
ALDH1A1 P00352 3/20 0.51
CNR2 P34972 2/20 0.51
CNR1 P21554 1/20 0.51
USP2 O75604 1/20 0.51
POLB P06746 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TP53 P04637 1/20 0.51
F2RL3 Q96RI0 1/20 0.51
CHRM1 P11229 1/20 0.50
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6246071 0.91 L3MBTL1 (0.56) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL9056926 0.86 LMNA (0.58) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL28034943 0.86 NR4A2 (0.55) L3MBTL1LMNANPSR1ALDH1A1TP53
SCHEMBL9030278 0.86 LMNA (0.61) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL28034304 0.81 CNR2 (0.56) ALDH1A1CNR2CNR1HSD17B10
SCHEMBL27556132 0.81 LMNA (0.56) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL28774126 0.80 PLA2G2A (0.49) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL27740513 0.80 LMNA (0.54) L3MBTL1LMNAMAPK1NPSR1ADORA1
SCHEMBL28034936 0.79 CDC25A (0.58) CNR2CNR1
SCHEMBL28034295 0.79 CDC25A (0.58) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924964-A Preparation method of tetrahydrocarbazole ring compound 四川轻化工大学 2023-10-24 CN claimed
EP-1146905-A1 COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN Algos Pharmaceutical Corporation (US) 2001-10-24 EP claimed
WO-2000029022-A1 COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS ALGOS PHARMACEUTICAL CORPORATION (US) 2000-05-25 WO claimed
WO-2000029023-A1 COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN ALGOS PHARMACEUTICAL CORPORATION (US) 2000-05-25 WO claimed
US-20260034071-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2026-02-05 US disclosed
US-12383508-B2 High-purity peg lipids and uses thereof MODERNATX, INC. (US) 2025-08-12 US disclosed
US-20250152518-A1 PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2025-05-15 US disclosed
EP-4509118-A2 HIGH-PURITY PEG LIPIDS AND USES THEREOF ModernaTX, Inc. (US) 2025-02-19 EP disclosed
US-12151029-B2 PEG lipids and uses thereof MODERNATX, INC. (US) 2024-11-26 US disclosed
US-20240377399-A1 COMPOSITIONS AND METHODS FOR MODULATING HYDROXYLATION OF ACC2 BY PHD3 PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-11-14 US disclosed
EP-3853305-B1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX INC (US) 2024-10-02 EP disclosed
US-11905525-B2 Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins MODERNATX, INC. (US) 2024-02-20 US disclosed
WO-2001015744-A9 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES BRIGHAM & WOMENS HOSPITAL (US) 2002-09-26 WO disclosed
EP-1212101-A1 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2002-06-12 EP disclosed
US-6376519-B1 ANTIINFLAMMATORY AGENTS, ANTICANCER AGENTS TEMPLE UNIVERSITY-OF THE COMMONWEALTH OF HIGHER EDUCATION 2002-04-23 US disclosed
EP-1146905-A1 COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN Algos Pharmaceutical Corporation (US) 2001-10-24 EP disclosed
WO-2001015744-A1 SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2001-03-08 WO disclosed
WO-2000029022-A1 COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS ALGOS PHARMACEUTICAL CORPORATION (US) 2000-05-25 WO disclosed
WO-2000029023-A1 COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN ALGOS PHARMACEUTICAL CORPORATION (US) 2000-05-25 WO disclosed
US-5604253-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS MERCK FROSST CANADA, INC. (CA) 1997-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152518-A1 PEG LIPIDS AND USES THEREOF LIPA, LIPG, LIPC L3MBTL1 1379/4885LMNA 1086/4885MAPK1 4115/4885
US-11905525-B2 Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins CD47, FCGR3B, MSR1 L3MBTL1 386/4885LMNA 1808/4885MAPK1 3491/4885
US-20260034071-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF LNPEP, AUP1, PLTP L3MBTL1 1280/4885LMNA 1776/4885MAPK1 1046/4885
US-12151029-B2 PEG lipids and uses thereof LIPA, LIPG, LNPEP L3MBTL1 1288/4885LMNA 1036/4885MAPK1 4078/4885
US-12383508-B2 High-purity peg lipids and uses thereof LIPA, HDLBP, PLTP L3MBTL1 1640/4885LMNA 2286/4885MAPK1 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.