SCHEMBL20098543

SCHEMBL20098543

CCOC(=O)c1cn(CC2CC2)nc1N

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
CSNK1D P48730 2/20 0.44
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PTGER4 P35408 1/20 0.38
TSHR P16473 1/20 0.38
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31352155 0.95 LMNA (0.58) LMNACSNK1DALDH1A1KDM4EMEN1
SCHEMBL21723872 0.84 LMNA (0.45) LMNACSNK1DKDM4ETP53TSHR
SCHEMBL22897231 0.84 LMNA (0.45) LMNACSNK1DTP53TSHRELANE
SCHEMBL21724351 0.83 LMNA (0.43) LMNACSNK1DKDM4EHSD17B10TP53
SCHEMBL175330 0.83 ALDH1A1 (0.46) CSNK1DALDH1A1KDM4EMEN1KMT2A
SCHEMBL30871860 0.82 LMNA (0.44) LMNAALDH1A1KDM4EMEN1KMT2A
SCHEMBL18412911 0.81 CRHR1 (0.35) LMNA
SCHEMBL31714691 0.81 LMNA (0.44) LMNAKDM4ETP53
SCHEMBL24612004 0.80 NOTUM (0.42)
SCHEMBL31714887 0.80 TEAD2 (0.43) CSNK1DALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 EP disclosed
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2021-01-05 US disclosed
US-10865215-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-12-15 US disclosed
US-20200223867-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2020-07-16 US disclosed
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2019-06-27 US disclosed
WO-2019067864-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-04-04 WO disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10865215-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 LMNA 2153/4885CSNK1D 1090/4885ALDH1A1 621/4885
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors SERPINB1, FURIN, HIF1AN LMNA 2715/4885CSNK1D 3890/4885ALDH1A1 3562/4885
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 LMNA 2153/4885CSNK1D 1090/4885ALDH1A1 621/4885
US-20250333424-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, IRF3 LMNA 3393/4885CSNK1D 1978/4885ALDH1A1 3515/4885
US-20200223867-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 LMNA 2153/4885CSNK1D 1090/4885ALDH1A1 621/4885
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS SERPINB1, FURIN, HIF1AN LMNA 2715/4885CSNK1D 3890/4885ALDH1A1 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.