Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142392 | 0.78 | P2RX7 (0.51) | MTORRPTORMLST8HTR7 | |
| SCHEMBL20139930 | 0.77 | MTOR (0.53) | ALDH1A1MEN1KMT2AHTTUSP2 | |
| SCHEMBL20141948 | 0.77 | SMN1; SMN2 (0.51) | ALDH1A1MEN1KMT2AHTTTSHR | |
| SCHEMBL20156931 | 0.77 | MTOR (0.51) | ALDH1A1USP2TSHRMTORRPTOR | |
| SCHEMBL20141688 | 0.76 | MTOR (0.48) | KMT2AHTTMTORRPTORMLST8 | |
| SCHEMBL20142241 | 0.75 | MTOR (0.61) | ALDH1A1MEN1KMT2AHTTUSP2 | |
| SCHEMBL20140202 | 0.75 | HTR7 (0.55) | ALDH1A1KDM4EHTR7 | |
| SCHEMBL20140044 | 0.75 | MTOR (0.54) | ALDH1A1MEN1KMT2AHTTMTOR | |
| SCHEMBL20140664 | 0.74 | MTOR (0.57) | ALDH1A1HTTMTORRPTORMLST8 | |
| SCHEMBL20140587 | 0.74 | MTOR (0.54) | ALDH1A1HTTUSP2MTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |