Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156931 | 0.79 | MTOR (0.51) | HTR7PARP1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL20141569 | 0.77 | RAB9A (0.46) | GBA1HTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL20140812 | 0.77 | ALDH1A1 (0.56) | HTR7MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20140202 | 0.76 | HTR7 (0.55) | HTR7ALDH1A1KDM4ENPSR1HTR1A | |
| SCHEMBL20140304 | 0.76 | GBA1 (0.44) | GBA1PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL20156963 | 0.76 | GBA1 (0.45) | GBA1PARP1MEN1KMT2A | |
| SCHEMBL20142392 | 0.76 | P2RX7 (0.51) | HTR7PARP1 | |
| SCHEMBL20140044 | 0.74 | MTOR (0.54) | HTR7PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL20142823 | 0.74 | CYP46A1 (0.48) | HTR7MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20141182 | 0.73 | PARP1 (0.48) | PARP1ALDH1A1KDM4ENPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |