SCHEMBL20182277

SCHEMBL20182277

CN1c2ccc(-c3ccccc3)cc2C(c2ccccc2)(c2ccccc2)c2cc(-c3ccccc3)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.40
BACE1 P56817 6/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
PKM P14618 1/20 0.37
CNR1 P21554 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
GAA P10253 2/20 0.35
PAX8 Q06710 1/20 0.35
MCL1 Q07820 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CTSD P07339 2/20 0.35
BACE2 Q9Y5Z0 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19001736 0.95 PGR (0.37) PGRBACE1SLC6A2SLC6A4SLC6A3
SCHEMBL14691262 0.92 LMNA (0.38) PGRBACE1SLC6A2SLC6A4PKM
SCHEMBL18810829 0.86 PGR (0.40) PGRBACE1SLC6A2SLC6A4PKM
SCHEMBL23372033 0.85 HTT (0.39) PGRPKMCNR1GPR55ALDH1A1
SCHEMBL23557728 0.85 MEN1 (0.39) PGRPKMCNR1GPR55ALDH1A1
SCHEMBL23980730 0.82 HTT (0.38) PGRPKMCNR1GPR55ALDH1A1
SCHEMBL17988023 0.82 PGR (0.44) PGRBACE1LMNAGAACTSD
SCHEMBL13827269 0.81 FAAH (0.41) SLC6A2SLC6A4SLC6A3PKMALDH1A1
SCHEMBL12723319 0.79 PKM (0.32) PGRPKMCNR1GPR55ALDH1A1
SCHEMBL12723296 0.79 PGR (0.43) PGRBACE1LMNAGAACTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
EP-3645501-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230046046-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-02-16 US disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
US-20220158101-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-05-19 US disclosed
WO-2022096172-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-05-12 WO disclosed
US-20200136045-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-04-30 US disclosed
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-11-21 US disclosed
WO-2019170572-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019170729-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019115577-A1 SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-06-20 WO disclosed
WO-2019048443-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
WO-2019048458-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
WO-2019020654-A1 SPIROBIFLUORENE DERIVATIVES FOR USE IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-31 WO disclosed
WO-2019002190-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-03 WO disclosed
WO-2018091435-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046046-A1 COMPOUNDS FOR ELECTRONIC DEVICES ETV6, CYP2C19, ESR1 PGR 681/4885BACE1 995/4885SLC6A2 739/4885
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 PGR 394/4885BACE1 2158/4885SLC6A2 604/4885
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM PGR 2050/4885BACE1 1863/4885SLC6A2 1256/4885
US-20220158101-A1 MATERIALS FOR ELECTRONIC DEVICES EED, EPHA6, ERCC1 PGR 527/4885BACE1 2347/4885SLC6A2 298/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 PGR 2192/4885BACE1 2061/4885SLC6A2 34/4885
US-20200136045-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, SDHB, HCN2 PGR 1557/4885BACE1 3986/4885SLC6A2 474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.