Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.36 |
| ▸ | TUBB | P07437 | 5/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026164 | 0.88 | LMNA (0.36) | EGFRZAP70KARS1ALDH1A1MAPT | |
| SCHEMBL2019511 | 0.88 | CSNK1E (0.35) | — | |
| SCHEMBL2016014 | 0.88 | KDM4A (0.32) | — | |
| SCHEMBL2021837 | 0.85 | ZAP70 (0.40) | TRPM8ZAP70KARS1ALDH1A1GAA | |
| SCHEMBL2027341 | 0.82 | MEN1 (0.36) | ZAP70KARS1GAAMAPTKMT2A | |
| SCHEMBL2020328 | 0.81 | MAPT (0.42) | EGFRMAPTCSF1R | |
| SCHEMBL2025118 | 0.80 | RAB9A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14136841 | 0.78 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2019721 | 0.76 | ADORA3 (0.37) | — | |
| SCHEMBL12482081 | 0.76 | CASP1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160215-A1 | Substituted Triazolo-Pyrazine Compounds | ARQULE, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160215-A1 | Substituted Triazolo-Pyrazine Compounds | MKI67, TP53, THPO | TUBB4A 1070/4885TUBB 851/4885TUBA3C 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.