SCHEMBL2034737

SCHEMBL2034737

CCCCN(C=O)CCCC.COC(C)OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699019 0.94 ADH1C (0.38) ADH1CADH1AADH4TSHR
SCHEMBL11699441 0.92 ADH1C (0.41) ADH1CADH1AADH4TSHR
SCHEMBL6653799 0.88 ADH1A (0.31) ADH1CADH1A
SCHEMBL26772 0.82 TSHR (0.41) ADH1CADH1AADH4TSHR
Butane SCHEMBL11523278 0.81 LMNA (0.44) ADH1CADH1AADH4
SCHEMBL7209887 0.80
SCHEMBL2035531 0.79
SCHEMBL270411 0.78 ADH1A (0.38) ADH1CADH1AADH4TSHR
SCHEMBL271668 0.78 ADH1C (0.47) ADH1CADH1AADH4TSHR
SCHEMBL10940372 0.78 TSHR (0.34) ADH1CADH1AADH4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 WO disclosed
US-20230416294-A1 DECITABINE ANALOGS FOR IMMUNOLOGICAL AND ONCOLOGICAL THERAPY THE JOHNS HOPKINS UNIVERSTY 2023-12-28 US disclosed
WO-2022035852-A1 DECITABINE ANALOGS FOR IMMUNOLOGICAL AND ONCOLOGICAL THERAPY THE JOHNS HOPKINS UNIVERSITY (US) 2022-02-17 WO disclosed
US-8552175-B2 Sulfur transfer reagents for oligonucleotide synthesis A.M. Chemicals, Inc. (US) 2013-10-08 US disclosed
US-20110137021-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS A.M. Chemicals, Inc. 2011-06-09 US disclosed
US-7847075-B2 2-Azapurine compounds and their use ROCHE MOLECULAR SYSTEMS, INC. (US) 2010-12-07 US disclosed
US-7723528-B2 Sulfur transfer reagents for oligonucleotide synthesis AM CHEMICALS LLC (US) 2010-05-25 US disclosed
US-20090306360-A1 2-AZAPURINE COMPOUNDS AND THEIR USE ROCHE MOLECULAR SYSTEMS, INC. (US) 2009-12-10 US disclosed
US-20090306358-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC 2009-12-10 US disclosed
WO-2009148719-A1 SULFER TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC (US) 2009-12-10 WO disclosed
EP-1214331-B1 2-AZAPURINE COMPOUNDS AND THEIR USE ROCHE DIAGNOSTICS GMBH (DE) 2006-10-11 EP disclosed
EP-1097939-B1 Method for the synthesis of isoguanosine and of its 2'-derivatives BAYER AG (US) 2004-02-11 EP disclosed
EP-0778898-B1 REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES BAYER AG (US) 2002-11-13 EP disclosed
US-20010026918-A1 Reduction of nonspecific hybridization by using novel base-pairing schemes COLLINS MARK L (US) 2001-10-04 US disclosed
US-6232462-B1 SYNTHESIS OF AN ISOGUANOSINE DERIVATIVE USED AS ANTISENSE AND APTAMER THERAPEUTICS AND DRUG DISCOVERY BAYER CORPORATION 2001-05-15 US disclosed
EP-1097939-A2 Method for the synthesis of isoguanosine and its 2'-derivatives Bayer Corporation (US) 2001-05-09 EP disclosed
US-6140496-A Precursors for deoxyribonucleotides containing non-standard nucleosides BENNER, STEVEN 2000-10-31 US disclosed
US-5780610-A OLIGONUCLEOTIDE APTAMERS INCLUDING COMPLEMENTARY NONNATURAL NUCLEOTIDE UNITS SIEMENS HEALTHCARE DIAGNOSTICS INC. 1998-07-14 US disclosed
US-5681702-A MINIMIZES BACKGROUND NOISE CHIRON CORPORATION (US) 1997-10-28 US disclosed
US-4046884-A N-(α-Aminoalkylidene)phosphor- and phosphonamidates, and method for controlling insects VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306358-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS POLRMT, TST, DNTT ADH1C 3080/4885ADH1A 3543/4885ADH4 2428/4885
US-20230416294-A1 DECITABINE ANALOGS FOR IMMUNOLOGICAL AND ONCOLOGICAL THERAPY CDA, DCTD, ADA ADH1C 2056/4885ADH1A 816/4885ADH4 1845/4885
US-20010026918-A1 Reduction of nonspecific hybridization by using novel base-pairing schemes UNG, SAMHD1, RNGTT ADH1C 467/4885ADH1A 725/4885ADH4 669/4885
US-20090306360-A1 2-AZAPURINE COMPOUNDS AND THEIR USE ADAR, AMPD2, NSUN2 ADH1C 2721/4885ADH1A 2106/4885ADH4 2081/4885
US-20110137021-A1 SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS TST, POLRMT, DNTT ADH1C 2805/4885ADH1A 3622/4885ADH4 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.