Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 6/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975110 | 0.91 | MEN1 (0.37) | MEN1KMT2ACCR2MAPK8MAPK10 | |
| SCHEMBL2873433 | 0.84 | MEN1 (0.36) | MEN1KMT2ACCR2MAPK8MAPK10 | |
| SCHEMBL9846302 | 0.84 | MEN1 (0.36) | MEN1KMT2ACCR2MAPK8MAPK10 | |
| SCHEMBL203795 | 0.83 | SMN1; SMN2 (0.44) | MEN1KMT2ARAB9AGAATSHR | |
| SCHEMBL203516 | 0.83 | RAF1 (0.39) | MEN1KMT2AMAPK8 | |
| SCHEMBL709625 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2ACCR2RAB9AGAA | |
| SCHEMBL8522022 | 0.81 | L3MBTL1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2873428 | 0.81 | KMT2A (0.36) | MEN1KMT2ACCR2MAPK8MAPK10 | |
| SCHEMBL29363262 | 0.81 | KMT2A (0.36) | MEN1KMT2ACCR2MAPK8MAPK10 | |
| SCHEMBL205371 | 0.80 | PIN1 (0.41) | RAB9AGAATSHRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185074-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-30 | — | — | US | disclosed |
| US-20150144027-A1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME | KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) | 2015-05-28 | — | — | US | disclosed |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2013-12-05 | — | — | US | disclosed |
| US-8445519-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2013-05-21 | — | — | US | disclosed |
| US-8409627-B2 | Particulate wood preservative and method for producing the same | OSMOSE, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8088801-B2 | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | MERIAL, INC. | 2010-09-30 | — | — | US | disclosed |
| EP-1755841-B1 | TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES | OSMOSE INC (US) | 2010-09-15 | — | — | EP | disclosed |
| US-7659228-B2 | Synergistic insecticide mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20090293761-A1 | Composition for wood treatment comprising an injectable aqueous wood preservative slurry having sparingly-soluble biocidal particles and pigments | OSMOSE, INC. | 2009-12-03 | — | — | US | disclosed |
| US-20050009883-A1 | Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. | UHR HERMANN (DE) | 2005-01-13 | — | — | US | disclosed |
| US-20040258768-A1 | An aqueous solution of injectable particles of sparingly soluble copper salts not easily leached, yet with sustained microbiocidal and insecticidal effectiveness; impregnation by injection | OSMOSE, INC | 2004-12-23 | — | — | US | disclosed |
| US-20030134857-A1 | Synergistic insecticide mixtures | UHR HERMANN (DE) | 2003-07-17 | — | — | US | disclosed |
| US-6197799-B1 | PLANT SAFENING AGENTS; PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| US-5990043-A | COMPRISES AT LEAST ONE INSECTICIDE SELECTED FROM TRIFLUMURON, FLUFENOXURON, FLUCYCLOXURON, HEXAFLUMURON, AND OTHERS; A CARRIER AND BINDER; PROTECTS ITEMS SUCH AS SHIP HULLS IN BRACKISH OR SEAWATER FROM BARNICLE INFESTATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5972971-A | WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0750542-A1 | COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES | BAYER AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| EP-0713485-A1 | THIOCARBAMOYL COMPOUNDS | BAYER AG (DE) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995024997-A1 | COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-21 | — | — | WO | disclosed |
| WO-1995004722-A1 | THIOCARBAMOYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | MEN1 3084/4885KMT2A 3142/4885CCR2 210/4885 |
| US-20030134857-A1 | Synergistic insecticide mixtures | CHRM3, CHRNA5, CHRNA2 | MEN1 3489/4885KMT2A 2309/4885CCR2 828/4885 |
| US-11185074-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | IFNG, TLR1, IDO1 | MEN1 2747/4885KMT2A 1539/4885CCR2 507/4885 |
| US-20050009883-A1 | Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. | CHRM3, CHRNA5, CHRNE | MEN1 3510/4885KMT2A 1583/4885CCR2 643/4885 |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | MEN1 3084/4885KMT2A 3142/4885CCR2 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.