Iodotubercidin

Iodotubercidin

SCHEMBL2043545

Nc1ncnc2c1c(I)cn2C1OC(CO)C(O)C1O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 16/20 0.83
SLC29A1 Q99808 1/20 0.75
DOT1L Q8TEK3 3/20 0.71
NPC1 O15118 1/20 0.71
GALR3 O60755 1/20 0.71
S1PR4 O95977 1/20 0.71
ALDH1A1 P00352 1/20 0.71
MAPT P10636 1/20 0.71
S1PR1 P21453 1/20 0.71
HTT P42858 1/20 0.71
RAB9A P51151 1/20 0.71
PAX8 Q06710 1/20 0.71
HASPIN Q8TF76 1/20 0.67
DCLK1 O15075 1/20 0.65
DAPK3 O43293 1/20 0.65
DYRK3 O43781 1/20 0.65
CDK1 P06493 1/20 0.65
ROS1 P08922 1/20 0.65
RPS6KB1 P23443 1/20 0.65
CDK2 P24941 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodotubercidin SCHEMBL12618424 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL2786488 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL12505209 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL29383008 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL319225 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL13021361 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL12652819 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL8328935 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL29375718 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3
Iodotubercidin SCHEMBL16978206 1.00 ADK (0.83) ADKSLC29A1DOT1LNPC1GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834401-B2 Treating and preventing diseases by modulating cell mechanics THE JOHNS HOPKINS UNIVERSITY (US) 2023-12-05 US disclosed
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION 2023-09-14 US disclosed
WO-2023039578-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION (US) 2023-03-16 WO disclosed
US-20220411458-A1 TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING Roche Sequencing Solutions, Inc. 2022-12-29 US disclosed
CN-115317614-B Application of ADK inhibitor in preparation of medicine for treating spinal cord injury 暨南大学 2022-12-27 CN disclosed
CN-115317614-A Application of ADK inhibitor in preparation of medicine for treating spinal cord injury 暨南大学 2022-11-11 CN disclosed
CN-114096540-A Translocation control elements, reporter codes, and other means for translocation control for nanopore sequencing 斯特拉托斯基因公司 2022-02-25 CN disclosed
US-20210338706-A1 ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) 2021-11-04 US disclosed
US-10294262-B2 7-deazapurine nucleosides for therapeutic uses INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2019-05-21 US disclosed
US-10188633-B2 Identification of small molecules that facilitate therapeutic exon skipping THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-29 US disclosed
US-7678892-B2 Dye-labeled ribonucleotide triphosphates APPLIED BIOSYSTEMS, LLC (US) 2010-03-16 US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-12-20 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed
US-7262029-B2 Dye-labeled ribonucleotide triphosphates APPLERA CORPORATION (US) 2007-08-28 US disclosed
EP-1480515-B1 INBRED EMBRYONIC STEM-CELL DERIVED MICE ARTEMIS PHARMACEUTICALS GMBH (DE) 2005-10-19 EP disclosed
EP-1480515-A2 INBRED EMBRYONIC STEM-CELL DERIVED MICE ARTEMIS Pharmaceuticals GmbH (DE) 2004-12-01 EP disclosed
US-20030204862-A1 Inbred embryonic stem-cell derived mice KUEHN RALF (DE) 2003-10-30 US disclosed
WO-2003073843-A2 INBRED EMBRYONIC STEM-CELL DERIVED MICE ARTEMIS PHARMACEUTICALS GMBH (DE) 2003-09-12 WO disclosed
WO-1994006438-A1 ADENOSINE ANALOGUES AND METHOD OF INCREASING ADENOSINE RELEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10188633-B2 Identification of small molecules that facilitate therapeutic exon skipping RBM17, SMN1; SMN2, SNRPA1 ADK 1993/4885SLC29A1 1465/4885DOT1L 4208/4885
US-10294262-B2 7-deazapurine nucleosides for therapeutic uses TPMT, TYMP, ENTPD5 ADK 221/4885SLC29A1 6/4885DOT1L 689/4885
US-20220411458-A1 TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING PHAX, DNTT, NSUN3 ADK 1704/4885SLC29A1 11/4885DOT1L 4195/4885
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER TP53, CD4, MCL1 ADK 3917/4885SLC29A1 3859/4885DOT1L 864/4885
US-11834401-B2 Treating and preventing diseases by modulating cell mechanics PKD1, MMP11, MMP13 ADK 3649/4885SLC29A1 1598/4885DOT1L 3887/4885
US-20210338706-A1 ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK PER2, CRY1, ADORA2A ADK 4/4885SLC29A1 450/4885DOT1L 1755/4885
US-20070293662-A1 Dye-labeled ribonucleotide triphosphates DUT, POLRMT, SAMHD1 ADK 327/4885SLC29A1 101/4885DOT1L 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.