SCHEMBL206812

SCHEMBL206812

CS/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
DGAT1 O75907 1/20 0.31
MIF P14174 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7865780 1.00 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
SCHEMBL133918 1.00 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
Sulfuric Acid SCHEMBL28494040 0.94 CA12 (0.33) KMT2ATDP1MAOAMAOBCA1
SCHEMBL2342887 0.86 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
SCHEMBL21359614 0.86 DGAT1 (0.31) DGAT1
SCHEMBL2823978 0.86 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
SCHEMBL2342888 0.86 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
SCHEMBL21359615 0.86 DGAT1 (0.31) DGAT1
SCHEMBL15177020 0.84 KMT2A (0.33) KMT2ANFKB1NFKB2RELATDP1
SCHEMBL14535778 0.84 APLNR (0.38) KMT2ATDP1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1096 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12285501-B2 Compound targeting norepinephrine transporter Higuchi, Takahiro (DE) 2025-04-29 US claimed
US-20230272006-A1 PEPTIDOMIMETICS AND METHOD OF SYNTHESIS THEREOF THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-08-31 US claimed
US-20230100243-A1 PEPTIDOMIMETICS AND METHOD OF SYNTHESIS THEREOF THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-03-30 US claimed
EP-3911372-B1 COMPOUND TARGETING NOREPINEPHRINE TRANSPORTER GUANGZHOU MIPHERE MEDICAL TECH CO LTD (CN) 2022-11-30 EP claimed
US-20220096667-A1 Compound Targeting Norepinephrine Transporter Guangzhou Miphere Medical Technology Co., Ltd. (CN) 2022-03-31 US claimed
EP-3682906-A1 COMPOUND TARGETING NOREPINEPHRINE TRANSPORTER Julius-Maximilians-Universität Würzburg (DE) 2020-07-22 EP claimed
US-9403855-B2 Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses ACADEMIA SINICA (TW) 2016-08-02 US claimed
US-20150368192-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES UNIV DEGLI STUDI GENOVA (IT) 2015-12-24 US claimed
EP-2935207-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES Universita' degli Studi di Genova (IT) 2015-10-28 EP claimed
EP-2568976-B1 ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES ACADEMIA SINICA (TW) 2015-09-30 EP claimed
US-7928063-B2 Analogs of human growth hormone-releasing hormone, their preparation and use INSTYTUT FARMACEUTYCZNY (PL) 2011-04-19 US claimed
US-20100234588-A1 SYNTHETIC METHOD FOR CERATAMINE A AND B AND ANALOGS THEREOF THE OHIO STATE UNIVERSITY (US) 2010-09-16 US claimed
EP-1442059-B1 ANALOGS OF HUMAN GROWTH HORMONE-RELEASING HORMONE, THEIR PREPARATION AND USE INST FARMACEUTYCZNY (PL) 2007-02-14 EP claimed
US-20060293328-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TIDWELL RICHARD R 2006-12-28 US claimed
EP-1736466-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents The University of North Carolina at Chapel Hill (US) 2006-12-27 EP claimed
US-20060264608-A1 Bi-directional synthesis of oligoguanidine transport agents NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-11-23 US claimed
US-6486174-B2 TREATMENT OF TUMOR GROWTH, METASTASIS, RESTENOSIS, OSTEOPOROSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, RHEUMATOID ARTHRITIS, SICKLE CELL ANEMIA, NERVE SYSTEM DISORDERS 3-DIMENSIONAL PHARMACEUTICALS, INC. 2002-11-26 US claimed
US-20020061885-A1 Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists 3-DIMENSIONAL PHARMACEUTICALS, INC. 2002-05-23 US claimed
WO-2002012193-A1 TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID ALKOXYGUANIDINES AS INTEGRIN ANTAGONISTS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2002-02-14 WO claimed
US-6344484-B1 TREATMENT OF TUMOR GROWTH, METASTASIS, OSTEOPOROSIS, RESTENOSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND RHEUMATOID ARTHRITIS 3-DIMENSIONAL PHARMACEUTICALS, INC. 2002-02-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230100243-A1 PEPTIDOMIMETICS AND METHOD OF SYNTHESIS THEREOF GMPS, PAM, SRM KMT2A 3273/4885NFKB1 2460/4885NFKB2 3537/4885
US-20220096667-A1 Compound Targeting Norepinephrine Transporter SLC6A2, SLC18A2, SLC6A3 KMT2A 2778/4885NFKB1 3578/4885NFKB2 3618/4885
US-20150368192-A1 A METHOD OF SYNTHESIZING CREATINE DERIVATIVES CKMT1A; CKMT1B, TNNI3, TNNT2 KMT2A 3110/4885NFKB1 4483/4885NFKB2 4514/4885
US-12285501-B2 Compound targeting norepinephrine transporter SLC6A2, SLC18A2, SLC6A3 KMT2A 2778/4885NFKB1 3578/4885NFKB2 3618/4885
US-20020061885-A1 Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists ITGAL, ITGAV, ITGB3 KMT2A 2591/4885NFKB1 2543/4885NFKB2 2068/4885
US-20100234588-A1 SYNTHETIC METHOD FOR CERATAMINE A AND B AND ANALOGS THEREOF NR0B2, NR2C2, HRH3 KMT2A 447/4885NFKB1 3263/4885NFKB2 3250/4885
US-20060264608-A1 Bi-directional synthesis of oligoguanidine transport agents SLC29A2, SLC1A5, SLC29A1 KMT2A 4248/4885NFKB1 1709/4885NFKB2 1903/4885
US-20230272006-A1 PEPTIDOMIMETICS AND METHOD OF SYNTHESIS THEREOF GMPS, PAM, SRM KMT2A 3273/4885NFKB1 2460/4885NFKB2 3537/4885
US-20060293328-A1 Linear dicationic terphenyls and their aza analogues as antiparasitic agents TPMT, TYMS, DDT KMT2A 1167/4885NFKB1 2003/4885NFKB2 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.