Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL5575718 | 1.00 | — | — | |
| Phenol SCHEMBL27533571 | 1.00 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL5574705 | 1.00 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL6902664 | 0.96 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL27899405 | 0.96 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL22191 | 0.96 | — | — | |
| Phenol SCHEMBL29843261 | 0.96 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL29636940 | 0.92 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL28584059 | 0.92 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL6366351 | 0.92 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609860-B1 | METHODS FOR MANUFACTURING PHENOXYETHANOL | BAUSCH HEALTH IRELAND LTD (IE) | 2025-08-27 | — | — | EP | claimed |
| CN-108484369-B | Treatment method of hexaphenoxycyclotriphosphazene industrial wastewater | 绵阳师范学院 | 2021-06-04 | — | — | CN | claimed |
| US-10941097-B2 | Methods for manufacturing phenoxyethanol | BAUSCH HEALTH IRELAND LIMITED (IE) | 2021-03-09 | — | — | US | claimed |
| US-20200199057-A1 | Methods for manufacturing phenoxyethanol | JPMORGAN CHASE BANK, N.A. | 2020-06-25 | — | — | US | claimed |
| EP-3609860-A1 | METHODS FOR MANUFACTURING PHENOXYETHANOL | Bausch Health Ireland Limited (IE) | 2020-02-19 | — | — | EP | claimed |
| WO-2018189385-A1 | METHODS FOR MANUFACTURING PHENOXYETHANOL | VALEANT PHARMACEUTICALS IRELAND LIMITED (IE) | 2018-10-18 | — | — | WO | claimed |
| US-20070129535-A1 | Linear polyphosphonates and methods of making | TRITON SYSTEMS, INC. (US) | 2007-06-07 | — | — | US | claimed |
| US-20060216828-A1 | Rapid-response reversible dry surface CO2 detector | MERCURY ENTERPRISE, INC. | 2006-09-28 | — | — | US | claimed |
| US-7056855-B1 | Liquid tetrabutyl ammonium phenolate formulation | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-06 | — | — | US | claimed |
| CN-1198780-C | Liquid preparation of tetrabutylammonium phenate | BAYER AG (DE) | 2005-04-27 | — | — | CN | claimed |
| US-20050038201-A1 | Process for increasing the molecular weight of polyamides | DEGUSSA AG (DE) | 2005-02-17 | — | — | US | claimed |
| WO-2004076537-A1 | LINEAR POLYPHOSPHONATES AND METHODS OF MAKING | TRITON SYSTEMS, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| US-20040167283-A1 | Linear polyphosphonates that exhibit an advantageous combination of properties, and methods related thereto | TRITON SYSTEM, INC. | 2004-08-26 | — | — | US | claimed |
| EP-1140757-B1 | LIQUID TETRABUTYL AMMONIUM PHENOLATE FORMULATION | BAYER AG (DE) | 2003-07-23 | — | — | EP | claimed |
| CN-1331665-A | Liquid tetrabutylammonium phenolate formulation | BAYER AG (DE) | 2002-01-16 | — | — | CN | claimed |
| EP-3609860-B1 | METHODS FOR MANUFACTURING PHENOXYETHANOL | BAUSCH HEALTH IRELAND LTD (IE) | 2025-08-27 | — | — | EP | disclosed |
| US-20250188206-A1 | BIO-BASED ETHYLENE FOR THE PRODUCTION OF BIO-BASED POLYMERS, COPOLYMERS, AND OTHER BIO-BASED CHEMICAL COMPOUNDS | XYLECO, INC. | 2025-06-12 | — | — | US | disclosed |
| EP-0437480-A4 | METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0437480-A1 | METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS. | COMMW SCIENT IND RES ORG (AU) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990003840-A1 | METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1990-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199057-A1 | Methods for manufacturing phenoxyethanol | COMT, HPD, PNMT | ACHE 1300/4885TDP1 2079/4885CYP3A4 30/4885 |
| US-10941097-B2 | Methods for manufacturing phenoxyethanol | COMT, HPD, PNMT | ACHE 1300/4885TDP1 2079/4885CYP3A4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.