Phenol

Phenol

SCHEMBL22191

[Na+].[O-]c1ccccc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL29843261 1.00 TDP1 (0.41)
Phenol SCHEMBL27899405 1.00 TDP1 (0.41)
Phenol SCHEMBL6902664 1.00 TDP1 (0.41)
Phenol SCHEMBL29087168 0.96
Phenol SCHEMBL29636940 0.96 TDP1 (0.39)
Phenol SCHEMBL28584059 0.96 TDP1 (0.39)
Phenol SCHEMBL11553267 0.96
Phenol SCHEMBL2076600 0.96 TDP1 (0.39)
Phenol SCHEMBL6366351 0.96 TDP1 (0.39)
Phenol SCHEMBL5575718 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16100 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121379932-B Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-117466960-B Synthesis process of tetraacetyl gastrodin BAIYUN SHANDONG TAISHANGQIU PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122071421-A Process for efficiently preparing acrylamide monomer by low-cost base catalytic pyrolysis 深圳有为技术控股集团有限公司 2026-05-22 CN claimed
CN-116715284-B Preparation method and application of low-cost self-doped sodium ion battery anode material 江苏正力新能电池技术股份有限公司 2026-05-19 CN claimed
CN-122059420-A Sodium sulfite and refining method thereof 宁夏天新药业有限公司 2026-05-19 CN claimed
CN-119529231-B Enclosed polyisocyanate and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-119462752-B Imidazole-phosphoramidite bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphoramidite bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-122036632-A Hydrazide nucleating agent in poly-p use of ethylene terephthalate 太原科技大学 2026-05-15 CN claimed
CN-122042836-A Method for in-situ cleaning chromatographic stationary phase with assistance of illumination 延边大学 2026-05-15 CN claimed
WO-2026101997-A1 CHEMICAL BINDING OF SURFACE POLYMER TO EPOXY MATERIAL YIELD ENGINEERING SYSTEMS, INC. (US) 2026-05-15 WO claimed
US-4101530-A REACTING ISOPHORONE DIISOCYANATE WITH POLYHYDROXYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US claimed
US-4088703-A AS CYCLOHEXANOL; HYDROGENATION USING NICKEL CATALYST, DISTILLATION ALLIED CHEMICAL CORPORATION (US) 1978-05-09 US claimed
US-4070354-A ALKALI METAL COMPOUND CATALYST, HEATING THE DOW CHEMICAL COMPANY (US) 1978-01-24 US claimed
US-4060563-A Process for preparing 2-allyl phenol THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-11-29 US claimed
US-4059617-A Synthesis of dimethylaminoethyl methylmethacrylate AMERICAN CYANAMID COMPANY (US) 1977-11-22 US claimed
US-4025466-A CATALYTIC MIXTURE OF FUSED HETEROCYCLIC COMPOUND CONTAINING AMIDINE GROUP AND SALT OF CARBOXYLIC ACID S.A. PRB (BE) 1977-05-24 US claimed
US-3954709-A Phenylethyl group containing resins for the synthesis of peptides THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 1976-05-04 US claimed
US-3948602-A Analytical method of monitoring air for chloromethyl ether THE DOW CHEMICAL COMPANY (US) 1976-04-06 US claimed
US-3944389-A Detection of chloromethyl methyl ether or bis-chloro-methyl ether THE DOW CHEMICAL COMPANY (US) 1976-03-16 US claimed
US-3932207-A Process for obtaining cellulose from ligno-cellulosic raw materials SOCIETE DE PROMOTION ET D'EXPLOITATION INDUSTRIELLES DE PROCEDES DE BREVETS S.A. (CH) 1976-01-13 US claimed