Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL22191 | 1.00 | — | — | |
| Phenol SCHEMBL29843261 | 1.00 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL27899405 | 1.00 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL29087168 | 0.96 | — | — | |
| Phenol SCHEMBL29636940 | 0.96 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL28584059 | 0.96 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL11553267 | 0.96 | — | — | |
| Phenol SCHEMBL2076600 | 0.96 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL6366351 | 0.96 | TDP1 (0.39) | TDP1CYP3A4ALDH1A1CA4CA2 | |
| Phenol SCHEMBL5575718 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526274-B1 | CATALYST SYSTEM | EPC ENGINEERING & TECH GMBH (DE) | 2022-08-03 | — | — | EP | claimed |
| EP-3526274-A1 | CATALYST SYSTEM | EPC Engineering & Technologies GmbH (DE) | 2019-08-21 | — | — | EP | claimed |
| US-4727175-A | Hydroxyphenoxyphosphazenes and a process for producing same | THE DOW CHEMICAL COMPANY (US) | 1988-02-23 | — | — | US | claimed |
| US-4297455-A | Process for the preparation of carbonic acid aryl esters of polyester-diols lengthened via carbonate groups and their use for the preparation of polyester-diol bis-diphenol carbonates and polyester/polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-27 | — | — | US | claimed |
| US-4217437-A | Process for the preparation of carbonic acid bis-diphenol esters of polyalkylene oxide-diols lengthened via carbonate groups and their use for the preparation of high-molecular, segmented polyether/polycarbonates which can be processed as thermoplastics | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | claimed |
| US-4216298-A | Process for the preparation of carbonic acid bis-diphenol esters of polyester-diols and their use for the preparation of high-molecular segmented polyester/polycarbonates which can be processed as thermoplastics | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | claimed |
| CN-121574357-A | Catalyst system | EPC工程与技术有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-12329647-B2 | Prosthetic femoral head and method of making the same | Lento Medical Inc. (US) | 2025-06-17 | — | — | US | disclosed |
| CN-119852333-A | Positive electrode material and preparation method thereof, positive electrode plate, positive electrode slurry and preparation method thereof, battery and electricity utilization device | 宁德时代新能源科技股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119119704-A | Polycarbonate resin film | 三菱化学株式会社 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119705-A | Polycarbonate resin film | 三菱化学株式会社 | 2024-12-13 | — | — | CN | disclosed |
| US-20240341962-A1 | PROSTHETIC FEMORAL HEAD AND METHOD OF MAKING THE SAME | Lento Medical Inc. (US) | 2024-10-17 | — | — | US | disclosed |
| CN-118679206-A | Method for producing curable resin | 三菱瓦斯化学株式会社 | 2024-09-20 | — | — | CN | disclosed |
| US-4255556-A | Preparation of poly(ester carbonate) by interfacial method | ALLIED CHEMICAL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0017740-A1 | Preparation of poly(ester carbonate) by interfacial method | ALLIED CORPORATION (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4222962-A | Process for preparing a substituted diphenoxybenzene | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-09-16 | — | — | US | disclosed |
| US-4217437-A | Process for the preparation of carbonic acid bis-diphenol esters of polyalkylene oxide-diols lengthened via carbonate groups and their use for the preparation of high-molecular, segmented polyether/polycarbonates which can be processed as thermoplastics | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | disclosed |
| US-4216298-A | Process for the preparation of carbonic acid bis-diphenol esters of polyester-diols and their use for the preparation of high-molecular segmented polyester/polycarbonates which can be processed as thermoplastics | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-4200433-A | Use of nickel phenolate of o,o'-bis(p-1,1,3,3-tetramethylbutylphenol)sulfone and a phosphite in dyeing polyolefins | AMERICAN CYANAMID COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4073774-A | Preparation of dichloroethylene polymers | GENERAL ELECTRIC COMPANY (US) | 1978-02-14 | — | — | US | disclosed |