Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 4/20 | 0.53 |
| ▸ | PARG | Q86W56 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL10938667 | 1.00 | PKLR (0.53) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| Ammonia Solution, Strong SCHEMBL6752114 | 0.90 | PKLR (0.50) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL305527 | 0.89 | PKLR (0.62) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL28367628 | 0.89 | PKLR (0.62) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL32662068 | 0.89 | PKLR (0.62) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL29384291 | 0.89 | PKLR (0.62) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| Potassium Ion SCHEMBL2784885 | 0.89 | PARG (0.59) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| Water SCHEMBL1976332 | 0.88 | PKLR (0.60) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| Water SCHEMBL30203790 | 0.88 | PKLR (0.60) | PKLRPARGSMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL2858677 | 0.86 | PARG (0.59) | PKLRPARGSMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977431-B2 | Dithiocarbamic esters | LANXESS DEUTSCHLAND GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20110015360-A1 | DITHIOCARBAMIC ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-01-20 | — | — | US | disclosed |
| US-7825193-B2 | Dithiocarbamic esters | LANXESS DEUTSCHLAND GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| US-20070078229-A1 | suitable for regulating the molecular weight during the polymerization of chloroprene and/or 2,3-dichlorobutadiene; compound purity; no sacrifice of polymerization rate; efficient; industrial scale | ARLANXEO DEUTSCHLAND GMBH (DE) | 2007-04-05 | — | — | US | disclosed |
| US-7169937-B2 | Dithiocarbamic esters | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |
| US-20040110964-A1 | Dithiocarbamic esters | ARLANXEO DEUTSCHLAND GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-0648788-B1 | Method for producing a polychloroprene latex | DENKI KAGAKU KOGYO KK (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5681891-A | COPOLYMERIZING CHLOROPRENE WITH AN ETHYLENICALLY UNSATURATED CARBOXYLIC ACID IN PRESENCE OF POLYVINYL ALCOHOL | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5661205-A | COPOLYMERIZED WITH AN ETHYLENICALLY UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF POLYVINYL ALCOHOL AND A GLYCOL ETHER; ADHESIVES | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0626398-B1 | Polychloroprene latex and its composition | DENKI KAGAKU KOGYO KK (JP) | 1996-11-06 | — | — | EP | disclosed |
| EP-0648788-A1 | Method for producing a polychloroprene latex | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0626398-A1 | Polychloroprene latex and its composition | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4839447-A | SODIUM DITHIONITE FORMADINESULFINIC ACID AND POTASSIUM PEROXYD ISULFATE REDOX INITIATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078229-A1 | suitable for regulating the molecular weight during the polymerization of chloroprene and/or 2,3-dichlorobutadiene; compound purity; no sacrifice of polymerization rate; efficient; industrial scale | DDT, DHPS, CBR3 | PKLR 629/4885PARG 233/4885SMN1; SMN2 4415/4885 |
| US-20040110964-A1 | Dithiocarbamic esters | DDT, DECR1, PCCA | PKLR 1679/4885PARG 300/4885SMN1; SMN2 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.