SCHEMBL20809306

SCHEMBL20809306

Cc1cc(C)cc(-c2cc(F)c3ccc(C)cc3n2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 5/20 0.39
PDE10A Q9Y233 1/20 0.39
GRM2 Q14416 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 4/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DHODH Q02127 2/20 0.35
NQO2 P16083 1/20 0.35
CYP1A2 P05177 1/20 0.35
ACHE P22303 3/20 0.35
BCHE P06276 2/20 0.34
GRIN1 Q05586 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809088 0.87 XDH (0.42) ALDH1A1KDM4EGRM2L3MBTL1MAPT
SCHEMBL20809090 0.87 KDM4E (0.47) ALDH1A1KDM4EL3MBTL1MAPTLMNA
SCHEMBL20809087 0.85 KDM4E (0.52) ALDH1A1KDM4EPDE10AGRM2L3MBTL1
SCHEMBL24796159 0.83 LMNA (0.45) ALDH1A1KDM4EPDE10AL3MBTL1MAPT
SCHEMBL13309775 0.83 PSMB5 (0.41) ALDH1A1KDM4EPDE10AGRM2L3MBTL1
SCHEMBL13399632 0.82 PDE10A (0.38) PDE10AGRM2SMN1; SMN2
SCHEMBL20809302 0.78
SCHEMBL13647122 0.78 KDM4E (0.55) ALDH1A1KDM4EPDE10AGRM2MAPT
SCHEMBL10078860 0.75 MBNL1 (0.36) PDE10ALMNAKMT2ASMN1; SMN2
SCHEMBL20809089 0.74 ALDH1A1 (0.51) ALDH1A1KDM4EL3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ALDH1A1 42/4885KDM4E 4362/4885PDE10A 3085/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ALDH1A1 42/4885KDM4E 4362/4885PDE10A 3085/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ALDH1A1 16/4885KDM4E 3879/4885PDE10A 3444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.