SCHEMBL20865636

SCHEMBL20865636

CCCC(CCC)C(=O)N1CCN(CCNP(=O)(OCC)OCC)CC1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.51
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.39
HRH2 P25021 1/20 0.33
HRH1 P35367 1/20 0.33
GLA P06280 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
ALDH1A1 P00352 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
POLB P06746 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26209114 0.90 CYP2C19 (0.49) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL20857024 0.85 CYP2C19 (0.55) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL20865637 0.77 CYP2C19 (0.48) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL20857027 0.77 CYP2C19 (0.61) CYP2C19TSHRUSP2LMNAALDH1A1
SCHEMBL22287259 0.75 CYP2C19 (0.43) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL22299758 0.73 CYP2C19 (0.53) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL20857025 0.73 CYP2C19 (0.48) CYP2C19TSHRUSP2HRH2HRH1
SCHEMBL24172011 0.71 THRB (0.47) CYP2C19USP2ALDH1A1
SCHEMBL21078258 0.70 HTR1A (0.46) CYP2C19TSHRHRH1ALDH1A1HSD17B10
SCHEMBL28898592 0.70 CYP2C19 (0.43) CYP2C19TSHRUSP2HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599599-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2026-04-14 US disclosed
EP-4578508-A2 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF Medicon Pharmaceuticals, Inc. (US) 2025-07-02 EP disclosed
EP-3687972-B1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS INC (US) 2025-04-09 EP disclosed
CN-117417281-A Anti-inflammatory, anti-cancer and anti-angiogenic compounds, pharmaceutical compositions and methods of making and using the same 麦迪康制药公司 2024-01-19 CN disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. 2024-01-18 US disclosed
CN-111655666-B Anti-inflammatory, anti-cancer and anti-angiogenic compounds, pharmaceutical compositions and methods of making and using the same 麦迪康制药公司 2023-11-07 CN disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof MEDICON PHARMACEUTICALS, INC. (US) 2023-09-12 US disclosed
US-20200246330-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICON PHARMACEUTICALS, INC. (US) 2020-08-06 US disclosed
WO-2019067974-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICALS COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF MEDICAL PHARMACEUTICALS, INC. (US) 2019-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599599-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof VEGFA, SLC10A6, LITAF CYP2C19 978/4885TSHR 4015/4885USP2 4009/4885
US-20200246330-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF VEGFA, HPGDS, ALOX5 CYP2C19 666/4885TSHR 4882/4885USP2 4384/4885
US-11752146-B2 Anti-inflammatory, anti-cancer, and anti-angiogenic compounds, pharmaceutical compositions, and methods of making and using thereof VEGFA, HPGDS, ALOX5 CYP2C19 666/4885TSHR 4882/4885USP2 4384/4885
US-20240016799-A1 ANTI-INFLAMMATORY, ANTI-CANCER, AND ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THEREOF VEGFA, HPGDS, ALOX5 CYP2C19 666/4885TSHR 4882/4885USP2 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.