Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20951588 | 0.86 | HRH4 (0.45) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| SCHEMBL31441000 | 0.74 | HTR6 (0.43) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| SCHEMBL1568098 | 0.68 | DRD2 (0.51) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| SCHEMBL8130625 | 0.67 | TRPA1 (0.66) | DRD2TRPA1HTR3AHTR1ACHRM2 | |
| Hydrochloric Acid SCHEMBL4234715 | 0.67 | DRD2 (0.50) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| Hydrochloric Acid SCHEMBL1773502 | 0.67 | DRD2 (0.50) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| SCHEMBL5565939 | 0.67 | CYP1A2 (0.47) | DRD2ADRB1HTR3AHTR1ACYP1A2 | |
| SCHEMBL3258474 | 0.65 | DRD2 (0.48) | DRD2ADRB1TRPA1HTR3AHTR1A | |
| SCHEMBL28762409 | 0.64 | ADRB1 (0.51) | DRD2ADRB1HTR3AHTR1ACYP1A2 | |
| SCHEMBL15263752 | 0.64 | HTR3A (0.44) | DRD2ADRB1HTR3AHTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518755-B2 | Stable solutions of multicyclic antidepressants | LEYDEN TECHNOLOGIES B.V. (NL) | 2022-12-06 | — | — | US | disclosed |
| US-20200290999-A1 | Stable solutions of multicyclic antidepressants | LEYDEN TECHNOLOGIES B.V. (NL) | 2020-09-17 | — | — | US | disclosed |
| EP-3691651-A1 | STABLE SOLUTIONS OF MULTICYCLIC ANTIDEPRESSANTS | Leyden Technologies B.V. (NL) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068859-A1 | STABLE SOLUTIONS OF MULTICYCLIC ANTIDEPRESSANTS | LEYDEN TECHNOLOGIES B.V. (NL) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518755-B2 | Stable solutions of multicyclic antidepressants | TPH1, BDNF, TPH2 | DRD2 27/4885ADRB1 259/4885TRPA1 2415/4885 |
| US-20200290999-A1 | Stable solutions of multicyclic antidepressants | TPH1, BDNF, TPH2 | DRD2 27/4885ADRB1 259/4885TRPA1 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.