Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20313914 | 0.96 | MAPT (0.55) | CA1CA2CA4CA6PKM | |
| SCHEMBL11683563 | 0.92 | ESR1 (0.56) | CA1CA2CA4CA6PKM | |
| SCHEMBL1604304 | 0.88 | PKM (0.55) | CA1CA2CA4CA6PKM | |
| SCHEMBL29942487 | 0.88 | PKM (0.55) | CA1CA2CA4CA6PKM | |
| Hydrochloric Acid SCHEMBL29565629 | 0.86 | PKM (0.53) | CA1CA2CA4CA6PKM | |
| SCHEMBL13761123 | 0.86 | PKM (0.46) | CA1CA2CA4CA6PKM | |
| SCHEMBL23864789 | 0.84 | SHBG (0.77) | CA1CA2CA4CA6PKM | |
| SCHEMBL13965866 | 0.84 | SHBG (0.47) | CA1CA2CA4CA6PKM | |
| SCHEMBL17058715 | 0.84 | CA1 (0.42) | CA1CA2CA4CA6PKM | |
| SCHEMBL18044786 | 0.82 | ALOX5 (0.46) | CA1CA2CA4CA6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2175863-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | Eastern Virginia Medical School (US) | 2010-04-21 | — | — | EP | claimed |
| WO-2009009625-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2009-01-15 | — | — | WO | claimed |
| US-20230173077-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | AJK Biopharmaceutical, LLC | 2023-06-08 | — | — | US | disclosed |
| WO-2021222807-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | AJK PHARMACEUTICAL LLC (US) | 2021-11-04 | — | — | WO | disclosed |
| US-9738678-B2 | Substituted nucleoside derivatives with antiviral and antimicrobial properties | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160311843-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2016-10-27 | — | — | US | disclosed |
| US-9296776-B2 | Substituted nucleoside derivatives with antiviral and antimicrobial properties | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296776-B2 | Substituted nucleoside derivatives with antiviral and antimicrobial properties | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2016-03-29 | — | — | US | disclosed |
| US-RE43067-E1 | Method for producing new polynuclear poly(formylphenol) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20110039798-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2011-02-17 | — | — | US | disclosed |
| US-20110039798-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2011-02-17 | — | — | US | disclosed |
| US-7875743-B2 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| US-7750190-B2 | reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| EP-2175863-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | Eastern Virginia Medical School (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20090182175-A1 | METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| WO-2009009625-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009009625-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173077-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | ELOVL6, FADS2, FASN | CA1 4751/4885CA2 4579/4885CA4 3765/4885 |
| US-20090182175-A1 | METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) | PCBP1, FPR2, PNKP | CA1 3768/4885CA2 2699/4885CA4 3455/4885 |
| US-20110039798-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | SAMHD1, TLR3, MAVS | CA1 4766/4885CA2 4820/4885CA4 4741/4885 |
| US-20160311843-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | SAMHD1, TLR3, MAVS | CA1 4766/4885CA2 4820/4885CA4 4741/4885 |
| US-20100016633-A1 | such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base | PAH, PGM2, HNMT | CA1 2391/4885CA2 1204/4885CA4 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.