SCHEMBL209120

SCHEMBL209120

Cc1cc(Cc2cc(C)c(O)c(C=O)c2)cc(C=O)c1O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 11/20 0.52
HMGB1 P09429 1/20 0.52
CXCL12 P48061 1/20 0.52
SHBG P04278 1/20 0.50
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CDK1 P06493 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31612192 1.00 ERN1 (0.52) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL31612191 1.00 ERN1 (0.52) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL27819945 0.91 HMGB1 (0.49) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL18218331 0.88 SHBG (0.72) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL2729835 0.87 LMNA (0.58) ERN1LMNAMAPT
SCHEMBL5647563 0.86 ERN1 (0.50) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL19640087 0.86 ERN1 (0.50) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL9174814 0.85 ERN1 (0.56) ERN1LMNAMAPTCDK1
SCHEMBL1275955 0.85 ERN1 (0.50) ERN1HMGB1CXCL12SHBGLMNA
SCHEMBL31346731 0.85 ERN1 (0.48) ERN1HMGB1CXCL12SHBGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-19 US disclosed
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7875743-B2 such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2011-01-25 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20100016633-A1 such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-01-21 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2007-10-04 US disclosed
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2007-10-04 US disclosed
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP ERN1 2895/4885HMGB1 1119/4885CXCL12 4541/4885
US-20070232839-A1 NOVEL POLYNUCLEAR POLYPHENOL COMPOUND TPR, PCNA, NCOA4 ERN1 3435/4885HMGB1 326/4885CXCL12 4528/4885
US-20120183751-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, POLR1G ERN1 2341/4885HMGB1 1533/4885CXCL12 3812/4885
US-20100016633-A1 such as bis(3-formyl-4-(4-methoxycarbonylphenyl)methoxyphenyl)methane, by reacting bis(hydroxymethyl-hydroxyphenyl)alkane with hexamethylene tetramine in presence of acid and hydrolyzing, then reacting with halogenated alkoxycarbonyl hydrocarbon in presence of base PAH, PGM2, HNMT ERN1 3647/4885HMGB1 669/4885CXCL12 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.