Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448668 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL9988818 | 0.81 | IMPDH2 (0.44) | ARIMPDH2IMPDH1SLC22A12 | |
| SCHEMBL28499705 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL28579068 | 0.73 | HPRT1 (0.40) | — | |
| SCHEMBL28575128 | 0.72 | TRPM4 (0.33) | — | |
| SCHEMBL29593037 | 0.72 | TAS2R14 (0.34) | AR | |
| SCHEMBL17441674 | 0.72 | SLC6A2 (0.37) | ARIMPDH2IMPDH1 | |
| SCHEMBL25658480 | 0.71 | TRPV4 (0.31) | — | |
| SCHEMBL2658980 | 0.71 | GABRA1 (0.32) | — | |
| SCHEMBL28426111 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266493-B2 | Thioacetate compounds, compositions and methods of use | ARDEA BIOSCIENCES, INC. (US) | 2019-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266493-B2 | Thioacetate compounds, compositions and methods of use | TXN, TXN2, XDH | AR 2358/4885IMPDH2 893/4885IMPDH1 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.