SCHEMBL20928641

SCHEMBL20928641

O=C(O)c1cc(S)nnn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 7/20 0.37
ACMSD Q8TDX5 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HCAR2 Q8TDS4 6/20 0.35
ALDH1A1 P00352 4/20 0.35
ASPH Q12797 2/20 0.35
KDM8 Q8N371 2/20 0.35
KDM6B O15054 1/20 0.35
TET3 O43151 1/20 0.35
KDM4A O75164 1/20 0.35
BBOX1 O75936 1/20 0.35
MAPT P10636 1/20 0.35
KDM5A P29375 1/20 0.35
KDM5C P41229 1/20 0.35
KDM4D Q6B0I6 1/20 0.35
TET2 Q6N021 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23819352 0.84 ALOX15 (0.48) ALOX15TSHRHIF1AKDM4EACMSD
Phosphoric Acid SCHEMBL30490531 0.75 CYTH3 (0.45) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL18167352 0.73 KMO (0.52) KDM4EALDH1A1ASPHKDM8KDM6B
SCHEMBL7373142 0.73 HCAR2 (0.43) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL10963802 0.68 KDM4E (0.41) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL13651832 0.68 ALOX15 (0.50) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL20929037 0.67 ALOX15 (0.38) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL10479187 0.67 ALOX15 (0.48) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL29199087 0.67 ALOX15 (0.61) ALOX15TSHRHIF1AKDM4EACMSD
SCHEMBL23425310 0.65 HCAR2 (0.43) ALOX15TSHRHIF1AKDM4EHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11022880-B2 Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound TOKYO OHKA KOGYO CO., LTD. (JP) 2021-06-01 US disclosed
US-20190121233-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2019-04-25 US disclosed
US-20160133857-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LT.D (KR) 2016-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190121233-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND CUTA, POLR1C, ASIC1 ALOX15 905/4885TSHR 1836/4885HIF1A 1571/4885
US-11022880-B2 Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound CUTA, POLR1C, ASIC1 ALOX15 905/4885TSHR 1836/4885HIF1A 1571/4885
US-20160133857-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, OCIAD1, TRPA1 ALOX15 594/4885TSHR 3642/4885HIF1A 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.