Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL30490531 | 0.89 | CYTH3 (0.45) | ALOX15TSHRHIF1AKDM4EACMSD | |
| SCHEMBL20928641 | 0.84 | ALOX15 (0.41) | ALOX15TSHRHIF1AKDM4EACMSD | |
| SCHEMBL7373142 | 0.82 | HCAR2 (0.43) | ALOX15TSHRHIF1AKDM4EACMSD | |
| SCHEMBL71141 | 0.73 | KMO (0.59) | ALOX15TSHRHIF1AKDM4EALDH1A1 | |
| SCHEMBL19897040 | 0.73 | — | — | |
| SCHEMBL698657 | 0.71 | KDM4E (0.52) | ALOX15TSHRHIF1AKDM4EACMSD | |
| SCHEMBL366003 | 0.71 | — | — | |
| SCHEMBL2705265 | 0.71 | ALOX15 (0.56) | ALOX15TSHRHIF1AKDM4EACMSD | |
| Fluoride SCHEMBL21173953 | 0.71 | KMO (0.57) | KDM4EALDH1A1ASPHKDM8KDM6B | |
| Hydrochloric Acid SCHEMBL3272233 | 0.71 | KMO (0.57) | KDM4EALDH1A1ASPHKDM8KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | AQP3, AQP4, AQP1 | ALOX15 1845/4885TSHR 4241/4885HIF1A 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.