Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL4378456 | 1.00 | SIRT6 (0.48) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Serine SCHEMBL22367625 | 1.00 | SIRT6 (0.48) | SIRT6ADORA3TSHRMC4RADRA1A | |
| D-Aspartate SCHEMBL4441146 | 0.84 | SIRT6 (0.47) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Aspartic Acid SCHEMBL20946365 | 0.84 | SIRT6 (0.47) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL28430357 | 0.82 | SLC1A5 (0.47) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL4378467 | 0.82 | SLC1A5 (0.47) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2635320 | 0.77 | SIRT6 (0.73) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL17712841 | 0.75 | SIRT6 (0.64) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2518992 | 0.75 | SIRT6 (0.42) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Serine SCHEMBL15878649 | 0.75 | SLC1A1 (0.54) | TSHRSLC1A1SLC7A5SLC1A3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120826-A | Method for monitoring mucosal healing | 麦迪贝肯有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117120826-A | Method for monitoring mucosal healing | 麦迪贝肯有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116419919-A | Subcutaneous and intramuscular administration of pyrazine compounds | 麦迪贝肯有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116348755-A | System and method for home percutaneous assessment of gastrointestinal function | 麦迪贝肯有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| CN-111481218-B | System and method for home transdermal GFR monitoring | 麦迪贝肯有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-115844391-A | Two-piece sensor assembly and method of use | 麦迪贝肯有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11602570-B2 | Compositions and systems for renal function determination | MEDIBEACON INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-11590244-B2 | Methods for renal function determination | MEDIBEACON INC. (US) | 2023-02-28 | — | — | US | disclosed |
| CN-111436947-B | Two-piece sensor assembly and method of using same | 麦迪贝肯有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-114555087-A | Anodic oxidation of 5-aminouracils | 麦迪贝肯有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3700578-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MediBeacon Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| CN-111481218-A | System and method for home transdermal GFR monitoring | 麦迪贝肯有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111436947-A | Two-piece sensor assembly and method of use | 麦迪贝肯有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-111298136-A | Use of transdermal glomerular filtration rate measurements in continuous renal replacement therapy | 麦迪贝肯有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-110545854-A | method for renal function determination | MEDIBEACON INC | 2019-12-06 | — | — | CN | disclosed |
| US-20190192694-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. | 2019-06-27 | — | — | US | disclosed |
| US-20190125902-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2019-05-02 | — | — | US | disclosed |
| US-20190125901-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11602570-B2 | Compositions and systems for renal function determination | GLS, ATP6V1B1, REN | SIRT6 1911/4885ADORA3 908/4885TSHR 1683/4885 |
| US-20190125902-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | GLS, REN, ATP6V1B1 | SIRT6 980/4885ADORA3 1623/4885TSHR 1110/4885 |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | GLS, ATP6V1B1, REN | SIRT6 1911/4885ADORA3 908/4885TSHR 1683/4885 |
| US-20190125901-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | GLS, ATP6V1B1, REN | SIRT6 1911/4885ADORA3 908/4885TSHR 1683/4885 |
| US-20190192694-A1 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | LIPG, FLT4, FABP3 | SIRT6 1659/4885ADORA3 757/4885TSHR 2040/4885 |
| US-11590244-B2 | Methods for renal function determination | GLS, REN, ATP6V1B1 | SIRT6 980/4885ADORA3 1623/4885TSHR 1110/4885 |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | GLS, SHBG, OGFR | SIRT6 2078/4885ADORA3 2212/4885TSHR 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.