Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586157 | 1.00 | HPGDS (0.54) | HPGDSPTPN1PIN1SMN1; SMN2RAB9A | |
| SCHEMBL1121702 | 0.87 | NPC1 (0.55) | HPGDSPTPN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30620888 | 0.85 | HMGCR (0.53) | PIN1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL9720553 | 0.85 | HMGCR (0.53) | PIN1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL5023065 | 0.84 | MRGPRX1 (0.47) | HPGDSPTPN1SMN1; SMN2PKMMAPT | |
| SCHEMBL23116699 | 0.83 | PIN1 (0.45) | PIN1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL20855539 | 0.83 | KMT2A (0.48) | PIN1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL2096737 | 0.83 | HPGDS (0.57) | HPGDSSMN1; SMN2LMNAGSK3BMEN1 | |
| SCHEMBL29622845 | 0.82 | KEAP1 (0.53) | PIN1SMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL113562 | 0.82 | KEAP1 (0.53) | PIN1SMN1; SMN2RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12593845-B2 | 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent | NIPPON SODA CO., LTD. (JP) | 2026-04-07 | — | — | US | disclosed |
| US-20240260575-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | NIPPON SODA CO., LTD. (JP) | 2024-08-08 | — | — | US | disclosed |
| US-20240114908-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | NIPPON SODA CO., LTD. (JP) | 2024-04-11 | — | — | US | disclosed |
| EP-4344545-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | Nippon Soda Co., Ltd. (JP) | 2024-04-03 | — | — | EP | disclosed |
| WO-2023017699-A1 | 3-SUBSTITUTED URACIL COMPOUND, AGRICULTURAL AND HORTICULTURAL GERMICIDE, NEMATICIDE, AND MEDICAL AND ANIMAL ANTIFUNGAL AGENT | 日本曹達株式会社 | 2023-02-16 | — | — | WO | disclosed |
| WO-2022230804-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | 日本曹達株式会社 | 2022-11-03 | — | — | WO | disclosed |
| WO-2022224924-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUND, AGRICULTURAL AND HORTICULTURAL ANTI-BACTERIAL AGENT, NEMATICIDE, AND ANTI-FUNGAL AGENT FOR MEDICAL AND VETERINARY USES | 日本曹達株式会社 | 2022-10-27 | — | — | WO | disclosed |
| EP-4053120-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | Nippon Soda Co., Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-114585610-A | 2, 6-dioxo-3, 6-dihydropyrimidine compound, and agricultural and horticultural bactericide, nematicide, and medical and animal antifungal agent | 日本曹达株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-108290902-B | Ester ACC inhibitors and uses thereof | 吉利德阿波罗公司 | 2021-08-31 | — | — | CN | disclosed |
| EP-2265606-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | disclosed |
| US-20090274652-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-05 | — | — | US | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |
| US-7579369-B2 | CB 1 receptor inverse agonists | HOFFMANN-LA ROCHE INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7294644-B2 | CB 1 receptor inverse agonists | HOFFMANN-LA ROCHE INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20070238754-A1 | Novel CB 1 receptor inverse agonists | MAYWEG ALEXANDER | 2007-10-11 | — | — | US | disclosed |
| EP-1583742-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-12 | — | — | EP | disclosed |
| US-20040167129-A1 | Novel CB 1 receptor inverse agonists | HOFFMANN-LA ROCHE INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2004060870-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12593845-B2 | 2,6-dioxo-3,6-dihydropyrimidine compound, agricultural and horticultural bactericide, nematicide, and medical and veterinary antifungal agent | CASP6, GMDS, HPD | HPGDS 1973/4885PTPN1 426/4885PIN1 1854/4885 |
| US-20240260575-A1 | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | CYP51A1, PIK3C3, AADAC | HPGDS 4836/4885PTPN1 126/4885PIN1 660/4885 |
| US-20090274652-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, PYGL | HPGDS 544/4885PTPN1 1786/4885PIN1 2196/4885 |
| US-20040167129-A1 | Novel CB 1 receptor inverse agonists | CNR1, CNR2, ARRB1 | HPGDS 1346/4885PTPN1 991/4885PIN1 4308/4885 |
| US-20070238754-A1 | Novel CB 1 receptor inverse agonists | CNR1, CNR2, GPR139 | HPGDS 1536/4885PTPN1 946/4885PIN1 4300/4885 |
| US-20240114908-A1 | 2,6-DIOXO-3,6-DIHYDROPYRIMIDINE COMPOUND, AGRICULTURAL AND HORTICULTURAL BACTERICIDE, NEMATICIDE, AND MEDICAL AND VETERINARY ANTIFUNGAL AGENT | BROX, HPD, DAXX | HPGDS 1433/4885PTPN1 1934/4885PIN1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.