Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.53 |
| ▸ | KDM5A | P29375 | 2/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.53 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14311707 | 0.84 | KDM4E (0.38) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL14306871 | 0.81 | ALDH1A1 (0.45) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL14294143 | 0.81 | KDM4E (0.35) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL8751997 | 0.81 | ADORA3 (0.41) | KDM4EKDM5AKDM3AJMJD1CTSHR | |
| SCHEMBL1505808 | 0.77 | KDM4E (0.57) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL87765 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL31126262 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL3560191 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL163233 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL1457909 | 0.74 | KDM4E (0.58) | KDM4EKDM5AKDM3AJMJD1CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903064-A | 2-Sulfonyl pyrimidine-4-carboxamide compound I and synthetic method thereof | 西北师范大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117903064-A | 2-Sulfonyl pyrimidine-4-carboxamide compound I and synthetic method thereof | 西北师范大学 | 2024-04-19 | — | — | CN | disclosed |
| US-20220193060-A1 | Inhibition of IL-1 Induced Inflammation | THIOLAB LLC (US) | 2022-06-23 | — | — | US | disclosed |
| US-11022880-B2 | Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-06-01 | — | — | US | disclosed |
| WO-2020223608-A1 | INHIBITION OF IL-1 AND IL-6 INFLAMMATION | THIOLAB, LLC, (US) | 2020-11-05 | — | — | WO | disclosed |
| US-20190121233-A1 | CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND | TOKYO OHKA KOGYO CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| US-20150287953-A1 | TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | Konica Minolta, Inc. (JP) | 2015-10-08 | — | — | US | disclosed |
| US-20150287953-A1 | TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | Konica Minolta, Inc. (JP) | 2015-10-08 | — | — | US | disclosed |
| US-8969365-B2 | Thiopyrimidinecarboxamides as CXCR1/2 modulators | SYNTRIX BIOSYSTEMS, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| EP-1383499-B1 | METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES | GRASSETTI FAMILY TRUST (US) | 2013-03-06 | — | — | EP | disclosed |
| US-8163776-B2 | Immunomodulation by administering thione-forming dithiobis-heterocyclic compound, increased natural killer cell activity, expansion of NK cell population, decreased B cell population, decreased antibody production | GRASSETTI FAMILY TRUST (US) | 2012-04-24 | — | — | US | disclosed |
| US-20040265327-A1 | Method of immunomodulation using thione-forming disulfides | GRASSETTI, DAVIDE | 2004-12-30 | — | — | US | disclosed |
| EP-1383499-A2 | METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES | Grassetti, Davide R. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002055080-A2 | METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES | GRASSETTI DAVIDE R (US) | 2002-07-18 | — | — | WO | disclosed |
| US-4378364-A | DITHIOBIS(PYRIDINE-CARBOXYLIC ACID) TO RELIEVE PAIN, INCREASE APPETITE | GRASSETTI DAVIDE R | 1983-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190121233-A1 | CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND | CUTA, POLR1C, ASIC1 | KDM4E 2101/4885KDM5A 966/4885KDM3A 730/4885 |
| US-11022880-B2 | Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound | CUTA, POLR1C, ASIC1 | KDM4E 2101/4885KDM5A 966/4885KDM3A 730/4885 |
| US-20040265327-A1 | Method of immunomodulation using thione-forming disulfides | TST, PBK, ICOS | KDM4E 3065/4885KDM5A 1849/4885KDM3A 3600/4885 |
| US-20220193060-A1 | Inhibition of IL-1 Induced Inflammation | IL1B, IL1A, IL6 | KDM4E 4132/4885KDM5A 3211/4885KDM3A 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.