Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21696535 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1GLANPC1SMN1; SMN2KMT2A | |
| SCHEMBL803252 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL16803055 | 0.76 | FFAR4 (0.37) | CYP3A4CYP2C9CYP2C19PTGS2KDM4E | |
| SCHEMBL19633940 | 0.76 | CHKA (0.35) | — | |
| SCHEMBL172423 | 0.75 | ACHE (0.48) | NPC1SMN1; SMN2KMT2AMEN1MAPK14 | |
| SCHEMBL12140863 | 0.74 | LMNA (0.38) | NPC1SMN1; SMN2LMNAMAPK14CYP2C19 | |
| SCHEMBL26046596 | 0.74 | PTGS2 (0.38) | NPC1AURKAABL1NTRK1LCK | |
| SCHEMBL17570168 | 0.73 | ACHE (0.46) | MAPK14PTGS2 | |
| SCHEMBL23373028 | 0.73 | ADH1B (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL13249626 | 0.73 | ALDH1A1 (0.42) | ALDH1A1NPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20220025265-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-27 | — | — | US | disclosed |
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-01-18 | — | — | US | disclosed |
| US-20210348056-A1 | Polymerisable Compounds and the Use thereof in Liquid-Crystal Displays | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | US | disclosed |
| US-11168257-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| US-20210284912-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| US-20210277310-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2021-09-09 | — | — | US | disclosed |
| US-11053442-B2 | Liquid crystal mixture and liquid crystal display | MERCK PATENT GMBH (DE) | 2021-07-06 | — | — | US | disclosed |
| US-10982150-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10934487-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| US-20200255740-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| US-20200157427-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-05-21 | — | — | US | disclosed |
| US-20200040257-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20190345389-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20190316037-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
| US-20190284474-A1 | SWITCHING LAYER FOR USE IN AN OPTICAL SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2019-09-19 | — | — | US | disclosed |
| US-20190264105-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-29 | — | — | US | disclosed |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | US | disclosed |
| US-20190241811-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-08 | — | — | US | disclosed |
| US-20190153320-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | ALDH1A1 4429/4885GLA 1271/4885NPC1 3628/4885 |
| US-20210284912-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | ALDH1A1 2963/4885GLA 2191/4885NPC1 345/4885 |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ALDH1A1 4429/4885GLA 1271/4885NPC1 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.