Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492832 | 0.85 | KEAP1 (0.52) | PGRHPGDSMN1; SMN2LMNACA1 | |
| Hydrochloric Acid SCHEMBL10526609 | 0.83 | KEAP1 (0.50) | PGRHPGDSMN1; SMN2LMNACA1 | |
| SCHEMBL29446941 | 0.83 | KEAP1 (0.50) | PGRHPGDCA1CA2CA9 | |
| SCHEMBL1200033 | 0.80 | ALDH1A1 (0.48) | PGRHTTHPGDLMNAGAA | |
| SCHEMBL28015271 | 0.78 | PGR (1.00) | PGRHTTHPGDFFAR1SMN1; SMN2 | |
| SCHEMBL11127847 | 0.75 | SOS1 (0.50) | PGRHTTHPGDFFAR1SMN1; SMN2 | |
| SCHEMBL13434501 | 0.75 | CA1 (0.47) | HPGDFFAR1SMN1; SMN2LMNACA1 | |
| SCHEMBL20041022 | 0.75 | HPGD (0.61) | PGRHTTHPGDSMN1; SMN2CA9 | |
| SCHEMBL3376915 | 0.74 | PGR (0.90) | PGRHTTHPGDFFAR1SMN1; SMN2 | |
| SCHEMBL251282 | 0.73 | KIF11 (0.50) | PGRCA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161437-A1 | PENDANT AMINES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | CELTAXSYS INC (US) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161437-A1 | PENDANT AMINES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | LTA4H, LTC4S, LTB4R | PGR 1116/4885HTT 3221/4885HPGD 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.