SCHEMBL21391744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22624250	0.91	NR1H4 (0.37)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19
	SCHEMBL24252993	0.90	NR1H4 (0.36)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19
	SCHEMBL21391604	0.90	NR1H4 (0.44)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19
	SCHEMBL21391762	0.86	L3MBTL1 (0.42)	L3MBTL1DPP4RAB9AALDH1A1HPGD
	SCHEMBL21387955	0.85	NR1H4 (0.33)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19
	SCHEMBL22624260	0.84	L3MBTL1 (0.47)	L3MBTL1MAPK1NPC1RAB9AALDH1A1
	SCHEMBL21391747	0.84	L3MBTL1 (0.47)	L3MBTL1MAPK1NPC1RAB9AALDH1A1
	SCHEMBL27341977	0.83	NR1H4 (0.34)	NR1H4
	SCHEMBL19762190	0.82	L3MBTL1 (0.52)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19
	SCHEMBL19762150	0.82	L3MBTL1 (0.52)	NR1H4L3MBTL1CYP1A2TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.