SCHEMBL21436612

SCHEMBL21436612

CCn1nc2cc(-c3cc4c5c(n(CC)nc5c3)-c3ccccc3C4=O)cc3c2c1-c1ccccc1C3=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ NPC1 O15118 5/20 0.36
▸ RAB9A P51151 5/20 0.36
▸ SMN1; SMN2 Q16637 5/20 0.36
▸ MAPK1 P28482 4/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ SLC9A1 P19634 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAOB P27338 3/20 0.35
▸ MAPK13 O15264 1/20 0.35
▸ EIF2AK2 P19525 1/20 0.35
▸ MAPK12 P53778 1/20 0.35
▸ MAPK11 Q15759 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12960431 0.75 MAPK13 (0.40) MAPTMEN1KMT2AAPEX1CYP1A2
SCHEMBL8176664 0.64 EIF2AK2 (0.66) MAPTMEN1KMT2AAPEX1CYP1A2
SCHEMBL13147782 0.64 EIF2AK2 (0.50) MAPTMEN1KMT2AAPEX1CYP1A2
SCHEMBL18122193 0.63 TOP2A (0.56) CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPK1
Anthraquinone SCHEMBL28260408 0.60 MEN1 (0.92) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL23422825 0.60 TOP2A (0.56) MAPTMEN1KMT2ACYP1A2CYP3A4
Anthraquinone SCHEMBL5550279 0.59 MAPT (0.67) MAPTMEN1KMT2AAPEX1CYP3A4
Anthraquinone SCHEMBL28215858 0.59 CDC25B (0.67) MAPTMEN1KMT2ACYP1A2CYP3A4
Anthraquinone SCHEMBL10902508 0.59 MEN1 (0.67) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL11236910 0.58 RAB9A (0.67) MAPTMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111304935-B Ink-jet printing colorant based on vat dye and preparation method thereof 青岛英杰泰新材料有限公司 2022-12-02 — — CN claimed
US-12585208-B2 Glittering toner, toner-storing unit, developer, developer-storing unit,image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2026-03-24 — — US disclosed
US-20260035579-A1 RYLENE-BASED UV CURABLE SECURITY INK COMPOSITIONS SICPA HOLDING SA (CH) 2026-02-05 — — US disclosed
CN-120442081-A Vat dye suitable for chinlon fabric and dyeing method 绍兴文理学院 2025-08-08 — — CN disclosed
US-12364659-B2 Multicomponent in situ coloration composition WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2025-07-22 — — US disclosed
CN-120202260-A Rylene-based UV curable security ink composition 锡克拜控股有限公司 2025-06-24 — — CN disclosed
US-20250114287-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2025-04-10 — — US disclosed
US-12201714-B2 Multicomponent pur composition WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2025-01-21 — — US disclosed
US-20240261213-A1 MULTICOMPONENT PUR COMPOSITION Wella International Operations Switzerland Sárl (CH) 2024-08-08 — — US disclosed
US-12053542-B2 Multicomponent silicone composition WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-08-06 — — US disclosed
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210145726-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-05-20 — — US disclosed
EP-3817710-A1 MULTICOMPONENT SILICONE COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3817825-A1 MULTICOMPONENT PUR COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3787753-A1 MULTICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-03-10 — — EP disclosed
EP-3773922-A1 BICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-02-17 — — EP disclosed
WO-2020114647-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-06-11 — — WO disclosed
WO-2020007511-A1 MULTICOMPONENT SILICONE COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2020007510-A1 MULTICOMPONENT PUR COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2019192916-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2019-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114287-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA MAPT 360/4885MEN1 2431/4885KMT2A 586/4885
US-12053542-B2 Multicomponent silicone composition CUTA, CD99, PLOD3 MAPT 2078/4885MEN1 10/4885KMT2A 648/4885
US-12364659-B2 Multicomponent in situ coloration composition KRT18, PRKDC, VIM MAPT 817/4885MEN1 1309/4885KMT2A 1653/4885
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION CUTA, CD99, PLOD3 MAPT 2078/4885MEN1 10/4885KMT2A 648/4885
US-12201714-B2 Multicomponent pur composition KRT18, EXOSC9, EXOSC4 MAPT 2254/4885MEN1 967/4885KMT2A 1904/4885
US-20240261213-A1 MULTICOMPONENT PUR COMPOSITION KRT18, EXOSC9, EXOSC4 MAPT 2254/4885MEN1 967/4885KMT2A 1904/4885
US-12585208-B2 Glittering toner, toner-storing unit, developer, developer-storing unit,image forming apparatus, and image forming method SP1, PAX2, SNAP23 MAPT 1066/4885MEN1 2917/4885KMT2A 3558/4885
US-20210145726-A1 BICOMPONENT COMPOSITION KRT18, EXOSC10, EXOSC9 MAPT 1247/4885MEN1 1869/4885KMT2A 1253/4885
US-20260035579-A1 RYLENE-BASED UV CURABLE SECURITY INK COMPOSITIONS RB1, CDK1, MARK1 MAPT 2133/4885MEN1 1765/4885KMT2A 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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