SCHEMBL21456850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29099370	0.88	KDM4E (0.72)	KDM4ELMNAHSP90AA1HTTSMN1; SMN2
	Hydrochloric Acid SCHEMBL9028799	0.83	KDM4E (0.77)	KDM4ELMNAHSP90AA1HTTSMN1; SMN2
	Bromide SCHEMBL9029591	0.83	KDM4E (0.83)	KDM4ELMNAHSP90AA1HTTSMN1; SMN2
	SCHEMBL7969197	0.83	—	—
	Bromide SCHEMBL7969935	0.81	KDM4E (0.62)	KDM4ELMNASMN1; SMN2ALDH1A1
	SCHEMBL29453936	0.77	PABPC1 (0.46)	KDM4ELMNAHTTRAD52APAF1
	SCHEMBL1238157	0.77	PABPC1 (0.46)	KDM4ELMNAHTTRAD52APAF1
	SCHEMBL17937170	0.76	KDM4E (0.72)	KDM4E
	SCHEMBL6115387	0.76	KDM4E (0.47)	KDM4EALDH1A1
	SCHEMBL42075	0.76	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.