Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | DHFR | P00374 | 4/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541996 | 0.88 | APP (0.46) | KCNH3APPDHFRDCPSBCHE | |
| SCHEMBL21542052 | 0.85 | DHFR (0.39) | APPDHFRDCPSBCHEACHE | |
| SCHEMBL21542046 | 0.84 | DHFR (0.44) | APPDHFRDCPSBCHEACHE | |
| Hydrochloric Acid SCHEMBL3779550 | 0.82 | KCNH3 (0.50) | KCNH3 | |
| SCHEMBL3638423 | 0.81 | KCNH3 (0.47) | KCNH3APPDHFRDCPSAURKA | |
| SCHEMBL21541976 | 0.80 | DCPS (0.44) | KCNH3APPDHFRDCPSBCHE | |
| Hydrochloric Acid SCHEMBL27786609 | 0.78 | DHFR (0.56) | DHFRDCPS | |
| SCHEMBL3640284 | 0.78 | NPC1 (0.40) | APPDHFRDCPSCTNNB1TCF7L2 | |
| SCHEMBL20564674 | 0.77 | KCNH3 (0.50) | KCNH3APPCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL3638075 | 0.76 | DRD3 (0.43) | GRK6CTNNB1TCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518760-B2 | Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2022-12-06 | — | — | US | disclosed |
| US-20190345157-A1 | COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345157-A1 | COMPOUNDS | ABCB11, LTC4S, AQP1 | HTR7 3923/4885ADRA1D 3800/4885HTR2C 2811/4885 |
| US-11518760-B2 | Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds | P2RX5, PNPO, P2RX3 | HTR7 3096/4885ADRA1D 3607/4885HTR2C 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.