Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.44 |
| ▸ | DCPS | Q96C86 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | GRK6 | P43250 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541976 | 0.85 | DCPS (0.44) | DHFRDCPSAPPBCHEACHE | |
| SCHEMBL21542012 | 0.84 | HTR7 (0.41) | DHFRDCPSAPPBCHEACHE | |
| SCHEMBL21541996 | 0.80 | APP (0.46) | DHFRDCPSAPPBCHEACHE | |
| SCHEMBL21542052 | 0.77 | DHFR (0.39) | DHFRDCPSAPPBCHEACHE | |
| SCHEMBL30493663 | 0.72 | ELANE (0.46) | DHFRDCPSAPPMAPK1ELANE | |
| SCHEMBL30092987 | 0.69 | BCHE (0.70) | APPBCHEACHEMAPK1ALDH1A1 | |
| SCHEMBL21567249 | 0.69 | BCHE (0.70) | APPBCHEACHEMAPK1ALDH1A1 | |
| SCHEMBL20399922 | 0.68 | CD38 (0.34) | MAPK1ALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL3779550 | 0.66 | KCNH3 (0.50) | MAPK1NPC1ALDH1A1RAB9A | |
| SCHEMBL4183660 | 0.65 | CACNA1G (0.43) | APPMAPK1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518760-B2 | Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2022-12-06 | — | — | US | disclosed |
| US-20190345157-A1 | COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345157-A1 | COMPOUNDS | ABCB11, LTC4S, AQP1 | DHFR 103/4885DCPS 672/4885APP 2829/4885 |
| US-11518760-B2 | Anti-Wolbachia pyrido[2,3-d]pyrimidine compounds | P2RX5, PNPO, P2RX3 | DHFR 78/4885DCPS 1048/4885APP 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.