SCHEMBL21554930

SCHEMBL21554930

CCCCCCCCCCC(O)CNCCN(CCNCC(O)CCCCCCCCCC)CCNCC(O)CCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.42
FFAR4 Q5NUL3 1/20 0.41
FFAR1 O14842 1/20 0.41
PLA2G1B P04054 3/20 0.38
PLA2G2A P14555 1/20 0.38
FAAH O00519 2/20 0.37
EPHX2 P34913 1/20 0.37
PSMD14 O00487 2/20 0.37
MMP2 P08253 2/20 0.37
ATG4B Q9Y4P1 2/20 0.37
HSP90AA1 P07900 1/20 0.37
ANPEP P15144 1/20 0.37
ERAP2 Q6P179 1/20 0.37
RAD52 P43351 1/20 0.37
SPHK1 Q9NYA1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24045753 1.00 GPR84 (0.42) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL25955602 1.00 GPR84 (0.42) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL10571376 0.93 PLA2G1B (0.43) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL19632306 0.92 L3MBTL1 (0.38) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL13964584 0.92 L3MBTL1 (0.38) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL13964581 0.92 L3MBTL1 (0.38) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL13964580 0.92 L3MBTL1 (0.38) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL13964583 0.92 L3MBTL1 (0.38) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL13829037 0.90 GPR84 (0.40) GPR84FFAR4FFAR1PLA2G1BPLA2G2A
SCHEMBL12515783 0.90 GPR84 (0.40) GPR84FFAR4FFAR1PLA2G1BPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac SE (DE) 2023-09-28 US disclosed
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac SE (DE) 2023-09-28 US disclosed
US-20230181713-A1 LASSA VIRUS VACCINE CureVac SE (DE) 2023-06-15 US disclosed
US-11524066-B2 Henipavirus vaccine CureVac SE (DE) 2022-12-13 US disclosed
US-20210401971-A1 MERS CORONAVIRUS VACCINE CUREVAC AG (DE) 2021-12-30 US disclosed
US-20210361761-A1 NOVEL YELLOW FEVER NUCLEIC ACID MOLECULES FOR VACCINATION CUREVAC AG (DE) 2021-11-25 US disclosed
US-11141476-B2 MERS coronavirus vaccine CUREVAC AG (DE) 2021-10-12 US disclosed
US-20210170017-A1 NOVEL RSV RNA MOLECULES AND COMPOSITIONS FOR VACCINATION CUREVAC AG (DE) 2021-06-10 US disclosed
US-20210069315-A1 FLAVIVIRUS VACCINE CureVac SE (DE) 2021-03-11 US disclosed
US-20210030864-A1 BUNYAVIRALES VACCINE CureVac SE (DE) 2021-02-04 US disclosed
US-20200179526-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac SE (DE) 2020-06-11 US disclosed
US-20190351044-A1 LASSA VIRUS VACCINE CureVac SE (DE) 2019-11-21 US disclosed
US-20190351047-A1 HENIPAVIRUS VACCINE CureVac SE (DE) 2019-11-21 US disclosed
US-20190351048-A1 MERS CORONAVIRUS VACCINE CureVac SE (DE) 2019-11-21 US disclosed
US-20190336608-A1 CATIONIC CARRIERS FOR NUCLEIC ACID DELIVERY CUREVAC AG (DE) 2019-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190351044-A1 LASSA VIRUS VACCINE LASP1, LAS1L, LTA GPR84 3725/4885FFAR4 3157/4885FFAR1 3048/4885
US-20190336608-A1 CATIONIC CARRIERS FOR NUCLEIC ACID DELIVERY HNRNPH3, CHMP4B, HNRNPH1 GPR84 3098/4885FFAR4 871/4885FFAR1 1311/4885
US-20190351047-A1 HENIPAVIRUS VACCINE NIPSNAP3A, NIPSNAP1, DHX35 GPR84 997/4885FFAR4 4503/4885FFAR1 4186/4885
US-20210030864-A1 BUNYAVIRALES VACCINE RNGTT, CHIA, TRMT1 GPR84 3353/4885FFAR4 3812/4885FFAR1 4054/4885
US-20200179526-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO HNRNPH1, HNRNPH3, SNRPE GPR84 2607/4885FFAR4 3141/4885FFAR1 3471/4885
US-20210361761-A1 NOVEL YELLOW FEVER NUCLEIC ACID MOLECULES FOR VACCINATION VIM, VARS1, ZFR GPR84 3666/4885FFAR4 4627/4885FFAR1 4702/4885
US-20190351048-A1 MERS CORONAVIRUS VACCINE SARS1, RNMT, ACE2 GPR84 1982/4885FFAR4 3611/4885FFAR1 3367/4885
US-11141476-B2 MERS coronavirus vaccine SARS1, RNMT, ACE2 GPR84 1982/4885FFAR4 3611/4885FFAR1 3367/4885
US-20210170017-A1 NOVEL RSV RNA MOLECULES AND COMPOSITIONS FOR VACCINATION RNASEH1, EXOSC9, SYNCRIP GPR84 672/4885FFAR4 4037/4885FFAR1 3452/4885
US-20230181713-A1 LASSA VIRUS VACCINE LASP1, LAS1L, LTA GPR84 3663/4885FFAR4 3169/4885FFAR1 3044/4885
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO HNRNPH1, HNRNPH3, SNRPE GPR84 2607/4885FFAR4 3141/4885FFAR1 3471/4885
US-20210069315-A1 FLAVIVIRUS VACCINE TLR9, DDX5, CHIA GPR84 722/4885FFAR4 4066/4885FFAR1 4086/4885
US-20210401971-A1 MERS CORONAVIRUS VACCINE SARS1, RNMT, ACE2 GPR84 1982/4885FFAR4 3611/4885FFAR1 3367/4885
US-11524066-B2 Henipavirus vaccine NIPSNAP3A, NIPSNAP1, DHX35 GPR84 997/4885FFAR4 4503/4885FFAR1 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.