Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170559 | 0.91 | SLC22A12 (0.47) | BRD4HTR6SLC22A12HTR1AHTR1B | |
| SCHEMBL2171141 | 0.86 | HTR6 (0.49) | BRD4BRD2HTR6UTS2R | |
| SCHEMBL2170067 | 0.85 | CCNT1 (0.50) | HTR6HTR2CCCNT1CDK9MAPT | |
| Hydrochloric Acid SCHEMBL2169494 | 0.84 | CCNT1 (0.49) | HTR6HTR2CCCNT1CDK9MAPT | |
| SCHEMBL2170359 | 0.83 | MAPT (0.48) | HTR6POLBCCNT1CDK9MAPT | |
| SCHEMBL2169880 | 0.82 | HTR6 (0.41) | BRD4BRD2HTR6POLBPTPN2 | |
| SCHEMBL2170768 | 0.80 | ESR1 (0.45) | HTR6POLBCCNT1CDK9MAPT | |
| SCHEMBL2170564 | 0.79 | HSD17B3 (0.48) | BRD4HTR6POLBCCNT1CDK9 | |
| SCHEMBL2170726 | 0.79 | HTR6 (0.49) | BRD4HTR6CCNT1CDK9 | |
| SCHEMBL2171609 | 0.78 | HTR6 (0.46) | HTR6HTR1AHTR1BHTR2CCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | claimed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | claimed |