SCHEMBL217308

SCHEMBL217308

Oc1ccc(Cc2cc(Cc3ccc(O)cc3)c(O)cc2O)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
KEAP1 Q14145 1/20 0.59
ESR1 P03372 2/20 0.59
ESR2 Q92731 2/20 0.59
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALOX5 P09917 2/20 0.55
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
TYR P14679 1/20 0.44
LTA4H P09960 1/20 0.43
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ABAT P80404 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14998892 0.90 MAPT (0.50) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL14564525 0.86 KEAP1 (0.50) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL278271 0.86 MAPT (0.50) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL278523 0.84 MAPT (0.78) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL16592194 0.82 ESR1 (0.61) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL8349574 0.82 ESR1 (0.61) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL10005890 0.82 ESR1 (0.61) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL19038934 0.81 ALOX5 (0.47) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL19038945 0.81 ALOX5 (0.47) MAPTKEAP1ESR1ESR2MEN1
SCHEMBL4055779 0.81 MAPT (0.81) MAPTKEAP1ESR1ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1623274-A2 PHOTORESIST COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2006-02-08 EP claimed
WO-2004088423-A2 PHOTORESIST COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-10-14 WO claimed
US-20040197704-A1 Photoresist compositions AZ ELECTRONIC MATERIALS USA CORP. 2004-10-07 US claimed
US-6790582-B1 NOVOLAK RESIN PARTIALLY ESTERIFIED WITH NAPHTHOQUINONEDIAZIDOSULFONYL GROUP; DILUTION RESIN(S), AND SOLVENT CLARIANT FINANCE BVI LIMITED (VG) 2004-09-14 US claimed
JP-8193053-A None JP disclosed
JP-7330646-A None JP disclosed
US-12497558-B2 Colour change composition and compounds THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-12-16 US disclosed
US-12297357-B2 Temperature-sensitive indicator THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-05-13 US disclosed
EP-3344468-B1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-03-05 EP disclosed
US-12202981-B2 Compound for use in colour change compositions SOCIETE BIC (FR) 2025-01-21 US disclosed
EP-3349990-B1 COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS SOCIéTé BIC (FR) 2024-10-30 EP disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-1296540-A1 DISPLAY TORAY INDUSTRIES, INC. (JP) 2003-03-26 EP disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
EP-1146394-A1 PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR IMPROVING DRY ETCHING RESISTANCE OF PHOTOSENSITIVE RESIN COMPOSITION CLARIANT INTERNATIONAL LTD. (CH) 2001-10-17 EP disclosed
US-6013407-A PHOTORESISTS WITH PHENOLIC RESINS, QUINONEDIAZIDE SULFONATES, PHOTOSENSITIVE AGENTS AND PHENOLIC COMPOUNDS NIPPON ZEON CO., LTD. (JP) 2000-01-11 US disclosed
EP-0831370-A1 POSITIVE RESIST COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-03-25 EP disclosed
JP-H08193053-A 1,3-BIS(4-T-BUTOXYCARBONYLMETHYLOXYPHENYLMETHYL)-4,6-BIS-T-BUTOXYCARBONYLMETHYLOXYBENZENE AND ITS DERIVATIVE SHIN ETSU CHEM CO LTD 1996-07-30 JP disclosed
JP-H07330646-A NEW POLYPHENOL AND PRODUCTION THEREOF HONSHU CHEM IND CO LTD 1995-12-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297357-B2 Temperature-sensitive indicator NCS1, TREH, NEFM MAPT 143/4885KEAP1 2900/4885ESR1 236/4885
US-12202981-B2 Compound for use in colour change compositions TYR, C1R, CBR3 MAPT 4055/4885KEAP1 1965/4885ESR1 413/4885
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM MAPT 3954/4885KEAP1 1098/4885ESR1 392/4885
US-12497558-B2 Colour change composition and compounds C5, C9, C3AR1 MAPT 1574/4885KEAP1 923/4885ESR1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.