Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 1/20 | 0.73 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | USP2 | O75604 | 4/20 | 0.79 |
| ▸ | HAT1 | O14929 | 4/20 | 0.79 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.79 |
| ▸ | HTT | P42858 | 4/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | RECQL | P46063 | 3/20 | 0.79 |
| ▸ | CASP7 | P55210 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | CASP1 | P29466 | 2/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | TST | Q16762 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | HBB | P68871 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Riboflavin SCHEMBL22034361 | 0.95 | MEN1 (0.85) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL535031 | 0.94 | MEN1 (0.87) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL50154 | 0.94 | MEN1 (0.87) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL27866166 | 0.94 | MEN1 (0.87) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL367680 | 0.93 | MEN1 (0.85) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL21805317 | 0.93 | MEN1 (0.89) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL296802 | 0.93 | MEN1 (0.89) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL618997 | 0.93 | MEN1 (0.89) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL27499698 | 0.92 | MEN1 (0.81) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL367681 | 0.92 | MEN1 (0.87) | MEN1KMT2AUSP2HAT1RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040621-A1 | COMPOSITION FOR PROMOTING DIFFERENTIATION OR PROLIFERATION OF HUMAN ADIPOSE STEM CELLS | 주식회사 엘지생활건강 | 2020-02-27 | — | — | WO | disclosed |