SCHEMBL21805959

SCHEMBL21805959

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)cnc3n2C)nc2cc(Cl)ccn12

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
PKM P14618 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 4/20 0.34
TRPA1 O75762 2/20 0.33
KMT2A Q03164 5/20 0.33
MEN1 O00255 4/20 0.33
NPSR1 Q6W5P4 3/20 0.33
DDR1 Q08345 4/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
XBP1 P17861 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29458412 1.00 POLB (0.40) POLBPKMMAPTALDH1A1TRPA1
SCHEMBL19711919 0.92 POLB (0.42) POLBPKMMAPTALDH1A1TRPA1
SCHEMBL29658140 0.89 GRM2 (0.31) POLB
SCHEMBL18737470 0.89 POLB (0.40) POLBPKMMAPTALDH1A1DDR1
SCHEMBL18737656 0.89 POLB (0.40) POLBPKMMAPTALDH1A1
SCHEMBL21561588 0.89 POLB (0.40) POLBPKMMAPTALDH1A1
SCHEMBL21805955 0.88 POLB (0.41) POLBPKMMAPTALDH1A1TRPA1
SCHEMBL29358501 0.88 POLB (0.41) POLBPKMMAPTALDH1A1TRPA1
SCHEMBL18737552 0.88 POLB (0.41) POLBPKM
SCHEMBL18737553 0.88 POLB (0.41) POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 US claimed
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 US claimed
WO-2024104813-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 WO claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP disclosed
US-12564191-B2 Pesticidal compounds BASF SE (DE) 2026-03-03 US disclosed
EP-4341258-B1 NEW SUBSTITUTED PYRIDINES AS FUNGICIDES BASF SE (DE) 2025-12-03 EP disclosed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US disclosed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP disclosed
US-20250019361-A1 (3-QUINOLYL)-QUINAZOLINE BASF SE (DE) 2025-01-16 US disclosed
WO-2021063735-A1 NEW BICYCLIC PYRIDINE DERIVATIVES BASF SE (DE) 2021-04-08 WO disclosed
EP-3769623-A1 MESOIONIC IMIDAZOLIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2021-01-27 EP disclosed
EP-3766879-A1 PESTICIDAL PYRAZOLE DERIVATIVES BASF SE (DE) 2021-01-20 EP disclosed
WO-2020244968-A1 FUNGICIDAL N-(PYRID-3-YL)CARBOXAMIDES BASF SE (DE) 2020-12-10 WO disclosed
WO-2020244970-A1 NEW CARBOCYCLIC PYRIDINE CARBOXAMIDES BASF SE (DE) 2020-12-10 WO disclosed
EP-3696177-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2020-08-19 EP disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 POLB 2837/4885PKM 1078/4885MAPT 1725/4885
US-12564191-B2 Pesticidal compounds CBR1, CBR3, SCN1B POLB 4047/4885PKM 3203/4885MAPT 3893/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885PKM 3372/4885MAPT 359/4885
US-20250019361-A1 (3-QUINOLYL)-QUINAZOLINE NQO2, MT-ND4L, MT-ND5 POLB 1645/4885PKM 2251/4885MAPT 1175/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 POLB 2186/4885PKM 1034/4885MAPT 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.