Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31690474 | 0.84 | TGFBR1 (0.52) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL7253429 | 0.83 | MAPT (0.61) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL342236 | 0.83 | MAPT (0.61) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL7256391 | 0.83 | MAPT (0.61) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL5125262 | 0.82 | FOLH1 (0.47) | MAPTFOLH1NAALAD2POLBALDH1A1 | |
| SCHEMBL26669597 | 0.80 | ALDH1A1 (0.68) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL3038972 | 0.79 | EPHX1 (0.64) | FOLH1SMN1; SMN2 | |
| SCHEMBL19929257 | 0.78 | FOLH1 (0.53) | MAPTFOLH1NAALAD2ALDH1A1LMNA | |
| SCHEMBL31410761 | 0.78 | POLB (0.44) | MAPTFOLH1NAALAD2POLBALDH1A1 | |
| SCHEMBL27827362 | 0.78 | POLB (0.44) | MAPTFOLH1NAALAD2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201152-A1 | COCRYSTAL ANTIOXIDANTS OF PROTOCATECHUIC ACID WITH L-THEANINE FOR THE TREATMENT OF OXIDATIVE STRESS AND INFLAMMATORY CONDITIONS | THEAPRIN PHARMACEUTICALS INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230201147-A1 | COCRYSTAL ANTIOXIDANTS OF PROTOCATECHUIC ACID WITH L-THEANINE FOR THE TREATMENT OF OXIDATIVE STRESS AND INFLAMMATORY CONDITIONS | THEAPRIN PHARMACEUTICALS INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230149427-A1 | COMPOSITIONS COMPRISING COCRYSTALS OF ACETYLSALICYLIC ACID AND THEANINE WITH TROMETHAMINE AND METHODS OF USE | THEAPRIN PHARMACEUTICALS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20200101010-A1 | SUBLINGUAL FORMULATION WITH WATER-SOLUBLE COCRYSTALS OF ACETYLSALICYLIC ACID WITH CITRIC ACID, SODIUM BICARBONATE, AND L-THEANINE FOR THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION | THEAPRIN PHARMACEUTICALS, INC. (US) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201152-A1 | COCRYSTAL ANTIOXIDANTS OF PROTOCATECHUIC ACID WITH L-THEANINE FOR THE TREATMENT OF OXIDATIVE STRESS AND INFLAMMATORY CONDITIONS | PTGES, MGST3, LPO | MAPT 2008/4885FOLH1 2141/4885NAALAD2 1837/4885 |
| US-20230149427-A1 | COMPOSITIONS COMPRISING COCRYSTALS OF ACETYLSALICYLIC ACID AND THEANINE WITH TROMETHAMINE AND METHODS OF USE | PTGIS, PTGES, PTGS1 | MAPT 1077/4885FOLH1 2195/4885NAALAD2 654/4885 |
| US-20230201147-A1 | COCRYSTAL ANTIOXIDANTS OF PROTOCATECHUIC ACID WITH L-THEANINE FOR THE TREATMENT OF OXIDATIVE STRESS AND INFLAMMATORY CONDITIONS | PTGES, MGST3, LPO | MAPT 2008/4885FOLH1 2141/4885NAALAD2 1837/4885 |
| US-20200101010-A1 | SUBLINGUAL FORMULATION WITH WATER-SOLUBLE COCRYSTALS OF ACETYLSALICYLIC ACID WITH CITRIC ACID, SODIUM BICARBONATE, AND L-THEANINE FOR THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION | CA3, ACSS2, CS | MAPT 3065/4885FOLH1 1343/4885NAALAD2 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.