Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18058760 | 0.89 | PTGS2 (0.41) | RPS6KA3RPS6KA2MAPTTP53MAPK1 | |
| SCHEMBL18058762 | 0.87 | HDAC8 (0.41) | RPS6KA3RPS6KA2ALDH1A1TSHRMAPT | |
| SCHEMBL18410384 | 0.86 | MAPT (0.41) | RPS6KA3RPS6KA2ALDH1A1TSHRMAPT | |
| SCHEMBL17576245 | 0.85 | AKR1C3 (0.44) | ALDH1A1MAPTNPC1RAB9ATP53 | |
| SCHEMBL15731795 | 0.83 | PIK3R1 (0.39) | ALDH1A1MAPTNPC1RAB9APOLB | |
| SCHEMBL20050092 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL6330031 | 0.82 | KMT2A (0.49) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1919863 | 0.82 | AKR1C3 (0.44) | ALDH1A1MAPTNPC1RAB9AATM | |
| SCHEMBL29483984 | 0.82 | RAD51 (0.51) | TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL186752 | 0.82 | LMNA (0.51) | ALDH1A1TSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590133-B2 | Dimer impurities of Apixaban and method to remove them | F.I.S.-FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590133-B2 | Dimer impurities of Apixaban and method to remove them | F2, FGB, F8 | RPS6KA3 2991/4885RPS6KA2 2447/4885PLK4 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.