SCHEMBL22731771

SCHEMBL22731771

C=C/C(=C\C=C(C)\C=C1/c2ccccc2Oc2cc(O)ccc21)CN

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.31
▸ USP2 O75604 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ HSP90AA1 P07900 1/20 0.31
▸ HSP90AB1 P08238 1/20 0.31
▸ BRCA1 P38398 1/20 0.31
▸ YWHAG P61981 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ KEAP1 Q14145 1/20 0.31
▸ NFE2L2 Q16236 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ TYR P14679 1/20 0.31
▸ CISD1 Q9NZ45 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31
▸ TOP1 P11387 1/20 0.30
▸ TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22731985 0.94 TYR (0.31) TYRMAOAMAOB
SCHEMBL22046148 0.66 MAOB (0.43) MEN1USP2POLBKMT2ATYR
SCHEMBL13542765 0.60 TYR (0.40) MEN1USP2POLBHSP90AA1HSP90AB1
SCHEMBL20099452 0.58 CRHBP (0.44) MEN1POLBKMT2ATYRCISD1
SCHEMBL22046626 0.58 MAOB (0.48) MEN1USP2POLBKMT2ATYR
SCHEMBL29958380 0.58 ATM (0.43) MEN1KMT2ATDP1MAOAMAOB
SCHEMBL28899441 0.58 ATM (0.43) MEN1KMT2ATDP1MAOAMAOB
SCHEMBL2114477 0.58 MAOA (0.49) MEN1USP2POLBHSP90AA1HSP90AB1
SCHEMBL24042749 0.57 CDK5 (0.46) MEN1USP2POLBHSP90AA1HSP90AB1
SCHEMBL26026796 0.57 MAOA (0.44) MEN1USP2POLBHSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MEN1 4768/4885USP2 1040/4885POLB 582/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS MEN1 4768/4885USP2 1040/4885POLB 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback