Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2809238 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL6230305 | 0.76 | ALDH1A1 (0.36) | — | |
| Methylene Chloride SCHEMBL7089348 | 0.72 | — | — | |
| SCHEMBL24769286 | 0.71 | GFER (0.35) | — | |
| SCHEMBL6750239 | 0.71 | KMT2A (0.41) | — | |
| SCHEMBL7256271 | 0.67 | — | — | |
| SCHEMBL6751984 | 0.67 | KDM4E (0.46) | — | |
| SCHEMBL9465959 | 0.66 | HPGD (0.33) | — | |
| SCHEMBL2901849 | 0.60 | — | — | |
| SCHEMBL11158135 | 0.59 | CA1 (0.42) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-114292221-A | Synthetic method and application of 2-aryl indole compound | 河北农业大学 | 2022-04-08 | — | — | CN | claimed |
| CN-104649996-B | Isothiazole oxime ether derivatives as well as preparation method and application thereof | 南开大学 | 2017-02-22 | — | — | CN | claimed |
| CN-105732606-A | Thiadiazole heterocycle-containing anabasine compound as well as preparation method and application thereof | 南开大学 | 2016-07-06 | — | — | CN | claimed |
| CN-103467463-B | One lignans analog derivative and its production and use | 南开大学 | 2016-06-22 | — | — | CN | claimed |
| CN-105669643-A | O-carboxamido benzamide derivative based on ryanodine receptor, and preparation method and application thereof | 江西天人生态股份有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105622597-A | Chloroisothiazole neonicotine compound, as well as preparation method and application thereof | UNIV NANKAI | 2016-06-01 | — | — | CN | claimed |
| CN-104650059-A | Thiazolone oxime ether derivatives, and preparation method and use thereof | UNIV NANKAI | 2015-05-27 | — | — | CN | claimed |
| CN-104649996-A | Isothiazole oxime ether derivatives as well as preparation method and application thereof | UNIV NANKAI | 2015-05-27 | — | — | CN | claimed |
| CN-104650061-A | Thiazole oxime ether compounds as well as preparation method and use thereof | UNIV NANKAI | 2015-05-27 | — | — | CN | claimed |
| CN-103232448-A | 4, 5-dihydro thiazole alcoholic ester derivative containing 4-methyl-1, 2, 3-thiadiazole and preparation method and application thereof | UNIV NANKAI | 2013-08-07 | — | — | CN | claimed |
| CN-103012392-A | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2013-04-03 | — | — | CN | claimed |
| CN-103012391-A | Pyrimidine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | ANIMAL PLANT AND FOOD TESTING CT OF TIANJIN ENTRY EXIT INSPECTION AND QUARANTIME BUREAU | 2013-04-03 | — | — | CN | claimed |
| CN-119080854-A | Cytidine nucleoside compound based on glycine, preparation method and application thereof, and bactericidal and antiviral composition | 沈阳农业大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-113480466-B | Indole substituted amide compound and preparation method and application thereof | 厦门大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-113929695-B | Sulfimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-104650059-A | Thiazolone oxime ether derivatives, and preparation method and use thereof | UNIV NANKAI | 2015-05-27 | — | — | CN | disclosed |
| CN-103232448-A | 4, 5-dihydro thiazole alcoholic ester derivative containing 4-methyl-1, 2, 3-thiadiazole and preparation method and application thereof | UNIV NANKAI | 2013-08-07 | — | — | CN | disclosed |
| CN-103012392-A | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2013-04-03 | — | — | CN | disclosed |
| CN-103012391-A | Pyrimidine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | ANIMAL PLANT AND FOOD TESTING CT OF TIANJIN ENTRY EXIT INSPECTION AND QUARANTIME BUREAU | 2013-04-03 | — | — | CN | disclosed |