Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271062 | 0.86 | LPAR1 (0.35) | RORCKDR | |
| SCHEMBL22270563 | 0.84 | WNT3A (0.39) | RORCKDRTP53MAPTLMNA | |
| SCHEMBL22270886 | 0.82 | L3MBTL1 (0.35) | ALDH1A1POLBMAPTLMNAPDE10A | |
| SCHEMBL22270671 | 0.82 | RORC (0.39) | RORCKDRSMN1; SMN2PDE10A | |
| SCHEMBL22270668 | 0.82 | KDR (0.36) | RORCALDH1A1POLBKDRTRPV1 | |
| SCHEMBL22270537 | 0.78 | MAPT (0.36) | ALDH1A1KDRTRPV1TP53MAPT | |
| SCHEMBL22270880 | 0.78 | LMNA (0.37) | ALDH1A1KDRTRPV1TP53MAPT | |
| SCHEMBL22271066 | 0.75 | RORC (0.35) | RORCMAPT | |
| SCHEMBL22270887 | 0.75 | KDM4E (0.40) | ALDH1A1TRPV1MAPTSMN1; SMN2 | |
| SCHEMBL22271048 | 0.72 | PDGFRB (0.41) | ALDH1A1TP53MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |