SCHEMBL2235170

SCHEMBL2235170

CC(=O)OC(=O)C(C)(C)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53
KCNN4 O15554 1/20 0.47
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17681414 0.90 MAPT (0.59) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL9676566 0.82 KCNN4 (0.46) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL4642200 0.82 KCNN4 (0.64) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL17681415 0.81 KMT2A (0.50) MAPTKMT2AKCNN4CYP2C19HIF1A
Phosphine SCHEMBL27280289 0.80 KCNN4 (0.62) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL6469118 0.80 CHRM3 (0.47) MAPTKMT2AKCNN4CYP2C19ALDH1A1
SCHEMBL28848759 0.80 KCNN4 (0.62) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL728471 0.79 KCNN4 (0.67) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL728468 0.79 MAPT (0.57) MAPTKMT2AKCNN4MAPK1CYP2C19
SCHEMBL9034523 0.79 MAPT (0.57) MAPTKMT2AKCNN4MAPK1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115443174-B Cosmetic composition containing low molecular weight amorphous polylactic acid resin 自然工作有限责任公司 2024-04-26 CN disclosed
EP-3416729-B1 PRO-FRAGRANCE COMPOSITION AQDOT LTD (GB) 2023-09-20 EP disclosed
US-20230234951-A1 CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2023-07-27 US disclosed
WO-2023036934-A1 CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYLPYRIDINE DERIVATIVES BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-03-16 WO disclosed
CN-111164194-B Structured unit dose cleaning products 路博润先进材料公司 2022-10-25 CN disclosed
EP-4059573-A1 SOLUBILISING AGENTS AND COMPOSITIONS COMPRISING SAME B&Sens (FR) 2022-09-21 EP disclosed
CN-109952116-B Solid non-aqueous gel air odorants 陶氏环球技术有限责任公司 2021-02-09 CN disclosed
CN-112218612-A Hair modification compositions and methods 路博润先进材料公司 2021-01-12 CN disclosed
US-10695277-B2 Pro-fragrance composition AQDOT LIMITED (GB) 2020-06-30 US disclosed
EP-3078365-B1 SOLUBILIZING AGENTS AND AQUEOUS COMPOSITIONS COMPRISING THEM DAITO KASEI IND FRANCE (FR) 2020-03-04 EP disclosed
US-20110217400-A1 BIOACTIVE COMPOSITION FOR COSMETIC APPLICATIONS EVONIK GOLDSCHMIDT GMBH (DE) 2011-09-08 US disclosed
WO-2011102001-A1 COSMETIC COMPOSITION L'OREAL (FR) 2011-08-25 WO disclosed
US-20100189664-A1 COSMETIC AGENTS BASED ON VINYLIMIDAZOLE POLYMERS BASF SE (DE) 2010-07-29 US disclosed
US-20100086574-A1 Use of aqueous emulsions in the form of foam for the reloading of textiles COGNIS IP MANAGEMENT GMBH (DE) 2010-04-08 US disclosed
US-20090104294-A1 BIOACTIVE COMPOSITION FOR COSMETIC APPLICATIONS EVONIK GOLDSCHMIDT GMBH (DE) 2009-04-23 US disclosed
US-20060008533-A1 Adsorbates containing active substances BASF AKTIENGESELLSCHAFT (DE) 2006-01-12 US disclosed
US-20050119150-A1 Portioned detergent composition HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-02 US disclosed
US-20040259751-A1 Dosed washing and cleaning agent composition HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-23 US disclosed
US-6432391-B1 FOR APPLICATION TO COSMETIC SUBSTRATES CHOSEN FROM HUMAN SKIN, KERATINOUS SUBSTANCES, SCALPS, AND LIPS, AND WHICH COMPRISES A LIQUID FATTY PHASE GELLED BY A FATTY POLYAMIDE L'ORéAL S.A. (FR) 2002-08-13 US disclosed
US-20020044918-A1 Transparent scented solid cosmetic composition L'OREAL S.A. (FR) 2002-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060008533-A1 Adsorbates containing active substances LIPA, HDLBP, APOB MAPT 2287/4885KMT2A 3788/4885KCNN4 3737/4885
US-20090104294-A1 BIOACTIVE COMPOSITION FOR COSMETIC APPLICATIONS CUTA, BMP2, BACH1 MAPT 1232/4885KMT2A 1555/4885KCNN4 4784/4885
US-20230234951-A1 CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES CYCS, CYP2E1, AHR MAPT 4415/4885KMT2A 3539/4885KCNN4 1221/4885
US-20100189664-A1 COSMETIC AGENTS BASED ON VINYLIMIDAZOLE POLYMERS PBRM1, VNN1, ADH5 MAPT 3058/4885KMT2A 555/4885KCNN4 3455/4885
US-20020044918-A1 Transparent scented solid cosmetic composition CUTA, FASN, ACADM MAPT 924/4885KMT2A 356/4885KCNN4 3109/4885
US-10695277-B2 Pro-fragrance composition COPS5, COPS8, CBR3 MAPT 3966/4885KMT2A 3712/4885KCNN4 2990/4885
US-20110217400-A1 BIOACTIVE COMPOSITION FOR COSMETIC APPLICATIONS CUTA, BMP2, BACH1 MAPT 1232/4885KMT2A 1555/4885KCNN4 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.