Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
| ▸ | GCKR | Q14397 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650910 | 0.90 | DRD3 (0.35) | AKR1C3PIK3CAMTOR | |
| SCHEMBL22650368 | 0.84 | ALOX5AP (0.37) | AKR1C3ALOX5APFEN1DDB1CRBN | |
| SCHEMBL29462389 | 0.84 | ALOX5AP (0.37) | AKR1C3ALOX5APFEN1DDB1CRBN | |
| SCHEMBL22650562 | 0.81 | PIK3CA (0.35) | AKR1C3PIK3CAMTORCPB1CHRNB2 | |
| SCHEMBL22650573 | 0.81 | LIPE (0.35) | DPP4ALOX5APFEN1GCKGCKR | |
| SCHEMBL22650412 | 0.75 | SPR (0.38) | PIK3CA | |
| SCHEMBL29491165 | 0.75 | SPR (0.38) | PIK3CA | |
| SCHEMBL22650571 | 0.72 | CCR5 (0.39) | — | |
| SCHEMBL22650730 | 0.72 | ALOX5AP (0.40) | AKR1C3ALOX5APFEN1PIK3CAMTOR | |
| SCHEMBL13768888 | 0.70 | CDK4 (0.46) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |