Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 8/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651402 | 0.80 | MAPT (0.61) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL1764460 | 0.79 | MAPT (0.60) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL4346795 | 0.74 | SLC9A1 (0.63) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL14796568 | 0.74 | SLC9A1 (0.79) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL7672503 | 0.73 | SLC9A1 (0.71) | MAPTNPC1RAB9ASLC9A1GLA | |
| Sulfuric Acid SCHEMBL31557704 | 0.72 | SLC9A1 (0.83) | MAPTNPC1RAB9ASLC9A1EGLN3 | |
| SCHEMBL7667065 | 0.72 | SLC9A1 (0.70) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL3428426 | 0.72 | NPC1 (1.00) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL17103011 | 0.70 | SLC9A1 (0.90) | MAPTNPC1RAB9ASLC9A1GLA | |
| SCHEMBL6850915 | 0.70 | SLC9A1 (0.71) | MAPTNPC1RAB9ASLC9A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867533-A | Cosmetic composition and use thereof | 美斯蒂克制药集团有限公司 | 2022-08-05 | — | — | CN | claimed |
| EP-3808411-A1 | COSMETIC COMPOSITIONS AND USE THEREOF | Mesoestetic Pharma Group, S.L. (ES) | 2021-04-21 | — | — | EP | claimed |
| WO-2020240056-A1 | COSMETIC COMPOSITIONS AND USE THEREOF | MESOESTETIC PHARMA GROUP, S.L (ES) | 2020-12-03 | — | — | WO | claimed |
| CN-114867533-A | Cosmetic composition and use thereof | 美斯蒂克制药集团有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3808411-A1 | COSMETIC COMPOSITIONS AND USE THEREOF | Mesoestetic Pharma Group, S.L. (ES) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020240056-A1 | COSMETIC COMPOSITIONS AND USE THEREOF | MESOESTETIC PHARMA GROUP, S.L (ES) | 2020-12-03 | — | — | WO | disclosed |