Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728296 | 0.90 | THRB (0.32) | — | |
| SCHEMBL22728291 | 0.81 | LMNA (0.37) | IDO1 | |
| SCHEMBL22728287 | 0.79 | RIPK1 (0.37) | — | |
| SCHEMBL22728363 | 0.77 | RIPK1 (0.40) | — | |
| SCHEMBL22728383 | 0.72 | CTSS (0.42) | — | |
| SCHEMBL22728334 | 0.72 | RIPK1 (0.41) | IDO1 | |
| SCHEMBL14307073 | 0.71 | IDO1 (0.37) | IDO1 | |
| SCHEMBL22728328 | 0.69 | HTR2A (0.47) | IDO1 | |
| Acetonitrile SCHEMBL29275405 | 0.68 | CA12 (0.42) | IDO1 | |
| SCHEMBL22728398 | 0.68 | PNMT (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |